Seroepidemiological survey of hepatitis B among healthy population in Mengjin district,Luoyang city
Objective To understand the positive rates of the serum markers of Hepatitis B virus(HBV)in the people living in Mengjin district of Luoyang city.Methods The questionnaire survey and blood samples were carried out in the selected people aged 1-79 years with multi-stage cluster random sampling method in Mengjin district of Luoyang city,2021.The surface antigen(HBsAg),surface antibody(HBsAb)and core antibody(HBcAb)of HBV in serum samples were tested with enzyme-linked immunosorbent assay(ELISA)method.If HBsAg was positive,the e antigen(HBeAg)and e antibody(HBeAb)of HBV were tested in the serum sample.Then the positive rate of the markers in the serum were be analyzed.Results The positive rate of HBsAg,HBsAb and HBcAb was 1.75％,60.48％and 18.25％,respectively in 630 subjects.Among the subjects with HBsAg positive,the positive rate of HBeAg and HBeAb was 9.09％and 81.82％.The positive rate of HBsAg was the highest in the age group of 40-79 years(4.12％),and the lowest in the age group of 1-years and 5-years(0.00％).There was statistical difference among the positive rates of HBsAg in different age groups(P=0.005).The positive rate of HBsAb was the highest in the age group of 1-years(92.50％),and the lowest in the age group of 5-years(44.12％).There was statistical difference among the positive rates of HBsAb in different age groups(x2=72.016,P＜0.001).The positive rates of HBsAb decreased as the inoculation time of final dose of hepatitis B vaccine lengthening(x2=84.961,P＜0.001).Conclusions The infection rate of HBV is relatively low in children in Mengjin district of Luoyang city.The adult HBV infectors still exist.The quality of routine immunization of Hepatitis B vaccine should be maintained in children,meanwhile vaccination of hepatitis B should be enhanced in adolescents and adults.
Hepatitis BHepatitis B virusHepatitis B vaccineSerum markerPositive rate
万方数据
维普
