首页|2018-2022年涡阳县手足口病流行特征及病原学监测分析

2018-2022年涡阳县手足口病流行特征及病原学监测分析

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目的 了解2018-2022年安徽省亳州市涡阳县手足口病(hand-foot-and-mouth disease,HFMD)流行趋势及病原学特征,为涡阳县HFMD的防控提供指导.方法 通过中国疾病预防控制信息系统收集2018-2022年涡阳县报告的HFMD病例、人口学信息以及HFMD病原实验室检测数据,采用描述流行病学方法分析涡阳县HFMD流行特征及病原学检测结果.结果 2018-2022年涡阳县累计报告HFMD 6 312例,发病率在37.64/10万~204.10/10万,年均发病率为99.71/10万,其中男性3 756例、占59.51%,女性2 556例、占40.49%,男女性别比为1.47∶1,男性年均发病率为116.32/10万,女性年均发病率为82.65/10万,5岁及以下儿童共报告6012例、占95.25%.每年报告HFMD发病数呈"双峰"分布.3-7月为第一个高峰期,累计报告病例3 968例、占62.86%;9-12月为第2个高峰期,累计报告病例1 709例、占27.08%.累计检测HFMD标本202份,肠道病毒阳性感染者共124例、占61.39%,其中CVA6病毒为60例、占48.39%,其他肠道病毒为35例、占28.23%.在新型冠状病毒肺炎疫情大流行之前(2018-2019年)与疫情常态化阶段(2020-2022年)病原学分型差异有统计学意义(x2=28.335,P<0.001).结论 涡阳县HFMD以5岁以下儿童为主,病原体主要为CVA6;应于高发季节前在托幼机构等重点场所做好健康教育和疫苗接种等防控措施,以有效预防HFMD的传播及流行.
Epidemiological characteristics and etiological surveillance results of hand-foot-mouth disease in Guoyang county from 2018 to 2022
Objective This paper aims to understand the epidemic trend and etiological characteristics of hand-foot-and-mouth disease(HFMD)from 2018 to 2022 in Guoyang county of Bozhou city,and to provide guidance for the prevention and control of HFMD in Guoyang county.Methods The HFMD cases,demographic information and HFMD pathogen laboratory test data reported in Guoyang county from 2018 to 2022 were collected through China Disease Prevention and Control Information System.Descriptive epidemiological methods were used to analyze the epidemic characteristics and etiological detection results of HFMD in Guoyang county.Results From 2018 to 2022,a total of 6 312 HFMD cases were reported in Guoyang county,with the incidence rate ranging from 37.64/100 000 to 204.10/100 000,and the average annual incidence rate was 99.71/100 000.Among them,there were 3 756 males(59.51%)and 2 556 females(40.49%),with a sex ratio of 1.47:1.The average annual incidence was 116.32/100 000 in males and 82.65/100 000 in females.A total of 6 012 cases(95.25%)were reported in children aged 5 and below.The number of HFMD cases reported annually has a"bimodal"distribution.The first peak period was from March to July,with a total of 3 968 cases,accounting for 62.86%.The second peak period was from September to December,with 1 709 cases reported,accounting for 27.08%.A total of 202 HFMD samples were detected in Guoyang county laboratory,and 124 cases(61.39%)were infected with enteroviruses,of which 60 cases(48.39%)were CVA6 viruses and 35 cases(28.23%)were other enteroviruses.There was a significant difference in pathogen types before the COVID-19 pandemic(2018-2019)and during the epidemic normalization stage(2020-2022)(x2=28.335,P<0.001).Conclusions HFMD is mainly found in children under 5 years old in Guoyang county,and CVA6 is the main pathogen.Prevention and control measures such as health education and vaccination should be taken in key places such as kindergartens before the high incidence season to effectively prevent the spread and epidemic of HFMD.

Hand,foot and mouth diseaseEpidemic characteristicsEtiology

刘廷杰、高静、高培、王宏

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安徽省涡阳县疾病预防控制中心,安徽涡阳 233600

涡阳县人民医院,安徽涡阳 233600

手足口病 流行特征 病原学

2024

疾病预防控制通报
新疆疾病预防控制中心

疾病预防控制通报

ISSN:1000-3711
年,卷(期):2024.39(4)