Analysis of viral load and its influencing factors among HIV/AIDS patients after antiretroviral therapy in Aksu prefecture
Objective To analyze the impact of HIV antiviral treatment on viral load(VL)and related factors in HIV/AIDS patients in Aksu prefecture of Xinjiang in 2023,and provide basis for improving the effect of antiviral treatment in local aear.Methods The prevalence state of HIV/AIDS patients who received antiviral treatment more than 6 months in 2023 were collected,and the results of single factor,binary Logistic regression were analyzed with the VL detection results.Results Among 2 599 treated HIV/AIDS patients,the results of VL were more than 1 000 copies/ml in 318 patients,with the virus suppression rate of 87.76％.The result of single factor analysis showed that there were statistical difference(P＜0.05)in different ages(x2=9.561),age of initiation of ART(x2=6.895)and duration of ART(x2=4.236).The results of multivariate Logistic regression showed that the age of ART initiation younger than 30 years(OR=1.592,95％CI:1.126-2.250)and the duration of ART shorter than 5 years(OR=1.316,95％CI:1.039-1.667)were the risk factors influencing the effects of antiviral therapy in HIV/AIDS patients.Conclusions The effect of antiviral therapy in HIV/AIDS patients were influenced by the age at initiation of ART and the duration of ART in Aksu prefecture of Xinjiang 2023.If the treatment time is earlier and longer,the virus suppression rate is higher,and the treatment effect is better.Special attention should be paid to HIV/AIDS patients who receive ART at the age younger than 30 years,and the duration of ART was shorter than 5 years in Aksu prefecture.The medication adherence should be improved,and the publicity of AIDS knowledge should be enhanced to increase the viral suppression rate.
万方数据
维普
