首页|肺结核与慢性阻塞性肺疾病相关性的Meta分析

肺结核与慢性阻塞性肺疾病相关性的Meta分析

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目的 分析肺结核和慢性阻塞性肺疾病(简称COPD)之间的相关关系并量化其关联程度,了解既往肺结核患者合并COPD的患病水平和危险因素,为肺结核合并COPD防治提供科学依据.方法 利用Meta分析方法,系统检索2000-2023年中国知网、万方数据、维普数据、Cochrane、Web of Science和PubMed数据库的国内外肺结核和COPD的相关文献.根据纳入和排除标准筛选文献,提取研究文献的设计类型、样本量、肺结核的COPD患者比例、无肺结核的COPD患者比例、OR等数据,使用Review Manager 5.4评估研究文章.结果 COPD、肺结核及其并发症相关2 922篇文献中,筛选符合条件24篇.肺结核患者患COPD的OR为2.97(95%CI:2.58~3.41,P<0.001),肺结核患者合并COPD的患病率为37%(95%CI:29%~45%,P<0.001).结论 肺结核患者罹患COPD的风险较高,肺结核合并COPD的患病率也较高,可能与吸烟、糖尿病和营养状况等因素有关;应控制烟草、使用气体燃料替代固体燃料,加强重点人群的防控并提高居民健康状况等措施,以降低合并症的患病率并改善疾病预后.
Meta-analysis of correlation between pulmonary tuberculosis and chronic obstructive pulmonary diseases
Objective To analyze the correlation between pulmonary tuberculosis and chronic obstructive pulmonary diseases(COPD)and the quantify of the relational degree,and understand the prevalence level and risk factors of COPD among previous pulmonary tuberculosis patients,then provide scientific basis for the prevention and treatment of pulmonary tuberculosis complicated with COPD.Methods The Meta-analysis was used to systematically search the domestic and foreign literatures on tuberculosis and COPD from China national knowledge infrastructure(CNKI),Wanfang Data,VIP Data,Cochrane,Web of Science,and PubMed databases during 2000 to 2023.The literatures were screened according to the inclusion and exclusion criteria,and the data such as the design type,sample size,proportion of COPD patients with pulmonary tuberculosis,proportions of the patients with COPD and the patients without tuberculosis,and odds ratios(OR)were extracted.The research articles were evaluated by the software of Review Manager 5.4.Results There were 24 articles met the criteria and screened out from 2 922 articles related to COPD,pulmonary tuberculosis and the complications.The OR value of pulmonary tuberculosis patients with COPD was 2.97(95%CI:2.58-3.41,P<0.001),and the prevalence rate of pulmonary tuberculosis patients with COPD was 37%(95%CI:29%-45%,P<0.001).Conclusions The risk level of suffering from COPD is high in the previous patients with pulmonary tuberculosis,and the prevalence rate is high too in the pulmonary tuberculosis patients who will complicate with COPD.The reasons may be related to the factors such as smoking,diabetes and nutritional status.Therefore,the measures of tobacco control,substitution of solid fuel to gas fuel,strengthening the level of prevention and control in the key population and improving the health status of residents could be carried out to decrease the prevalence rate of complications and improve the disease prognosis.

Pulmonary tuberculosisChronic obstructive pulmonary diseasesRisk factorsMeta-analysis

马晓薇、帕力旦·阿不都热合曼、王森路、王希江

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新疆医科大学公共卫生学院,乌鲁木齐 830017

新疆维吾尔自治区疾病预防控制中心,乌鲁木齐 830002

肺结核 慢性阻塞性肺疾病 风险因素 Meta分析

2024

疾病预防控制通报
新疆疾病预防控制中心

疾病预防控制通报

ISSN:1000-3711
年,卷(期):2024.39(6)