Comparison of Ligands in Palladium-catalyzed Electrochemical Allyl 4-Pyridinylation
4-CN-pyridine is a widely applied 4-pyridinylation reagent for diverse transformations.Conventionally,the reac-tion proceeds via an open-shell radical cross-coupling pathway.Following our previous study,in this work,we report the Pd-catalyzed allyl 4-pyrinylation reaction under electrochemical conditions.The reaction proceeds via radical-polar crossover pathway in which the role of phosphine ligand in reactivity and selectivity was extensively investi-gated.
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