Highly Sensitive Detection of Strontium Ions Using Metal-Organic Frameworks Functionalized Solid-state Nanochannels
Strontium-90,a highly radioactive isotope,accumulates within the food chain and skeletal structure,posing signif-icant risks to human health.There is a critical need for a sensitive detection strategy for Strontium-90 in complex environmental samples.Here,solid-state nanochannels,modified with metal-organic frameworks(MOF)and specific aptamers,were engineered for highly sensitive detection of strontium ion(Sr2+).The synergistic effect between the reduced effective diameter of the nanochannels due to MOF and the specific binding of Sr2+by aptamers amplifies the difference in ionic current signals,enhancing detection sensitivity significantly.The MOF-modified nanochannels exhibit highly sensitive detection of Sr2+,with a limit of detection(LOD)being 0.03 nmol·L-1,whereas the LOD for anodized aluminum oxide(AAO)without the modified MOF nanosheets is only 1000 nmol.L-1.These findings indicate that the LOD of Sr2+detected by the MOF-modified nanochannels is approximately 33,000 times higher than that by the nanochannels without MOF modification.Additionally,the highly reliable detection of Sr2+in various water samples was achieved,with a recovery rate ranging from 94.00％to 118.70％.This study provides valuable insights into the rapidly advancing field of advanced nanochannel-based sensors and their diverse applications for analyzing complex samples,including environmental contaminant detection,food analysis,medical diagnostics,and more.
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