Foundation models for bioinformatics

扫码查看

原文链接

万方数据
维普

外文摘要：Transformer-based foundation models such as ChatGPTs have revolu-tionized our daily life and affected many fields including bioinformatics.In this perspective,we first discuss about the direct application of textual foundation models on bioinformatics tasks,focusing on how to make the most out of canonical large language models and mitigate their inherent flaws.Meanwhile,we go through the transformer-based,bioinformatics-tailored foundation models for both sequence and non-sequence data.In particular,we envision the further development directions as well as chal-lenges for bioinformatics foundation models.

外文关键词：

ChatGPTfoundation modelslarge language modelstransformer

作者：

Ziyu Chen、Lin Wei、Ge Gao

展开 >

作者单位：

State Key Laboratory of Protein and Plant Gene Research,School of Life Sciences,Biomedical Pioneering Innovative Center(BIOPIC)& Beijing Advanced Innovation Center for Genomics(ICG),Center for Bioinformatics(CBI),Peking University,Beijing,China

Changping Laboratory,Beijing,China

出版年：

2024

DOI：

10.1002/qub2.69

定量生物学(英文版)

ISSN：

年,卷(期)：2024.12(4)