首页|Different bactericidal abilities of plasma-activated saline with various reactive species prepared by surface plasma-activated air and plasma jet combinations
Different bactericidal abilities of plasma-activated saline with various reactive species prepared by surface plasma-activated air and plasma jet combinations
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Plasma-activated water(PAW),as an extended form of cold atmospheric-pressure plasma,greatly expands the application of plasma-based technology.The biological effects of PAW are closely related to the aqueous reactive species,which can be regulated by the activation process.In this study,surface plasma-activated air(SAA)and a He+O2 plasma jet(Jet)were parallelly combined(the SAA+Jet combination)or sequentially combined(the SAA → Jet combination and the Jet → SAA combination)to prepare plasma-activated saline(PAS).The PAS activated by the combinations exhibited stronger bactericidal effects than that activated by the SAA or the Jet alone.The concentrations of H2O2 and NO2- were higher in the PAS activated by the Jet →SAA combination,while ONOO-concentrations were close in the three kinds of PAS and 1O2 concentrations were higher in the PAS activated by the SAA+Jet combination.The analysis of scavengers also demonstrated that H2O2,1O2,and ONOO-in the PAS activated by the SAA+Jet combination,and 1O2 in the PAS activated by the Jet → SAA combination played critical roles in bactericidal effects.Further,the effective placement time of the three PAS varied,and the PAS activated by the Jet → SAA combination could also inactivate 2.6-log1o of MRSA cells after placement for more than 60 min.The regulation of reactive species in plasma-activated water via different combinations of plasma devices could improve the directional application of plasma-activated water in the biomedical field.
plasma-activated watersurface plasma-activated airplasma jetbactericidal effectreactive species
贾怡康、李甜会、张瑞、赵鹏瑜、王子丰、陈旻、郭莉、刘定新
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State Key Laboratory of Electrical Insulation and Power Equipment,Center for Plasma Biomedicine,Xi'an Jiaotong University,Xi'an 710049,People's Republic of China
School of Life Science and Technology,Xi'an Jiaotong University,Xi'an 710049,People's Republic of China