首页|Different bactericidal abilities of plasma-activated saline with various reactive species prepared by surface plasma-activated air and plasma jet combinations

Different bactericidal abilities of plasma-activated saline with various reactive species prepared by surface plasma-activated air and plasma jet combinations

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Plasma-activated water(PAW),as an extended form of cold atmospheric-pressure plasma,greatly expands the application of plasma-based technology.The biological effects of PAW are closely related to the aqueous reactive species,which can be regulated by the activation process.In this study,surface plasma-activated air(SAA)and a He+O2 plasma jet(Jet)were parallelly combined(the SAA+Jet combination)or sequentially combined(the SAA → Jet combination and the Jet → SAA combination)to prepare plasma-activated saline(PAS).The PAS activated by the combinations exhibited stronger bactericidal effects than that activated by the SAA or the Jet alone.The concentrations of H2O2 and NO2- were higher in the PAS activated by the Jet →SAA combination,while ONOO-concentrations were close in the three kinds of PAS and 1O2 concentrations were higher in the PAS activated by the SAA+Jet combination.The analysis of scavengers also demonstrated that H2O2,1O2,and ONOO-in the PAS activated by the SAA+Jet combination,and 1O2 in the PAS activated by the Jet → SAA combination played critical roles in bactericidal effects.Further,the effective placement time of the three PAS varied,and the PAS activated by the Jet → SAA combination could also inactivate 2.6-log1o of MRSA cells after placement for more than 60 min.The regulation of reactive species in plasma-activated water via different combinations of plasma devices could improve the directional application of plasma-activated water in the biomedical field.

plasma-activated watersurface plasma-activated airplasma jetbactericidal effectreactive species

贾怡康、李甜会、张瑞、赵鹏瑜、王子丰、陈旻、郭莉、刘定新

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State Key Laboratory of Electrical Insulation and Power Equipment,Center for Plasma Biomedicine,Xi'an Jiaotong University,Xi'an 710049,People's Republic of China

School of Life Science and Technology,Xi'an Jiaotong University,Xi'an 710049,People's Republic of China

National Natural Science Foundation of China

51977174

2024

等离子体科学和技术(英文版)
中国科学院合肥物质科学研究所 中国力学学会

等离子体科学和技术(英文版)

EI
影响因子:0.297
ISSN:1009-0630
年,卷(期):2024.26(1)
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