Role of Macrophage Metabolic Reprogramming in Inflammation-Cancer Transformation
Inflammation-cancer transformation is a key link in the process of tumorigenesis and development. Recent studies have found that the metabolic reprogramming of macrophages,as the main constituent cells in the immune system,plays an important role in the inflammation-cancer transformation of tumors. In-depth study of the relationship between macrophage metabolic reprogramming and tu-mor inflammation-cancer transformation is of great significance for elucidating the mechanism of tumor malignant evolution . This review summarizes the research progress of macrophage metabolic reprogramming and tumor inflammation-cancer transformation,in order to ex-plore the potential application prospect of targeting macrophage metabolic reprogramming in tumor therapy.
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