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输血相关性移植物抗宿主病的研究进展

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输血相关性移植物抗宿主病(transfusion-associated graft-versus-host disease,TA-GVHD)是一种罕见且致命的输血并发症,由免疫反应引起,通常在输血后2~30 d内发生,发病率极低(0。01%~0。1%),但死亡率极高(≥90%),至今尚无有效的治疗方法。本文就TA-GVHD的发病机制、诊断、预防及治疗进行综述,为TA-GVHD的诊断和预防奠定基础。
Research Progress in Transfusion-Associated Graft-Versus-Host
Transfusion-associated graft-versus-host(TA-GVHD)is a rare but fatal complication of blood transfusion. It is caused by an immune response and usually occurs 2 to 30 days after blood transfusion. The incidence is extremely low(0.01%-0.1%),but the mortal-ity rate is extremely high(≥90%),and there is no effective treatment so far. This article reviews the pathogenesis,diagnosis,prevention and treatment of TA-GVHD,laying the foundation for the diagnosis and prevention of TA-GVHD.

transfusion-related graft-versus-host diseasemechanismdiagnosisprevention

张贵彬

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通化市人民医院,吉林 通化 134000

输血相关的移植物抗宿主病 机制 诊断 预防

吉林省卫健委卫生健康科技能力提升项目吉林省科技厅自然科学基金项目

2021JC048YDZJ202201ZYTS282

2024

吉林医药学院学报
吉林医药学院

吉林医药学院学报

影响因子:0.459
ISSN:1673-2995
年,卷(期):2024.45(5)