首页|A novel small-animal locomotor activity recording device for biological clock research

A novel small-animal locomotor activity recording device for biological clock research

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原文链接
  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
The rodent running-wheel recording apparatus is a reliable approach for studying cir-cadian rhythm.This study demonstrated how to construct a simple and intelligent running-wheel recording system.The running wheel was attached to the cage's base,whereas the Hall sensor was attached to the cage's cover.Then,the RJ25 adaptor relayed the running signal to the main control board.Finally,the main control board was connected to the USB port of the computer with the USB connection.Data were collected using the online-accessible,self-created software Magturning.Through Magturning,generated data were saved and exported in real time.Afterward,the device was validated by collecting data on the locomotor activities of mice under dif-ferent light conditions.In conclusion,this new device can record circadian activity of rodents.Our device is appropriate for interdisciplinary investigations related to biological clock research.

biological clockcircadian rhythmintelligent equipmentlocomotor activityrunning wheel

Yi-Long Wu、Ming Zhong、Jun Yin、Wei-Jie Ou、Yu-Bin Zhuang、Nan-Wen Zhang、Su Lin、Yue-Yong Zhu

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Endoscopy Center,The First Affiliated Hospital,Fujian Medical University,Fuzhou,China

Department of Endocrinology,The First Affiliated Hospital,Fujian Medical University,Fuzhou,China

Chuangke Workshop Technology Co.,Ltd,Shenzhen,China

Department of Digestive Nutrition,Fujian Children's Hospital,Fuzhou,China

Experimental Animal Center,Fujian Medical University,Fuzhou,China

Department of Pharmacology,Fujian Medical University,Fuzhou,China

Department of Hepatology,Hepatology Research Institute,Clinical Research Center for Liver and Intestinal Diseases of Fujian Province,The First Affiliated Hospital,Fujian Medical University,Fuzhou,China

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Startup Fund for scientific research,Fujian Medical UniversityJoint Funds for the Innovation of Science and Technology in Fujian Province of ChinaJoint Funds for the Innovation of Science and Technology in Fujian Province of China

2020QH10392020Y91142020Y9119

2024

10.1002/ame2.12381

动物模型与实验医学(英文)
中国实验动物学会,中国医学科学院医学实验动物研究所

动物模型与实验医学(英文)

ISSN：2096-5451
年,卷(期)：2024.7(1)
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