Abstract
Tendon calcification is a common clinical condition that frequently occurs as a complication after tendon injury and surgery,or as an expression of fibrodysplasia ossificans progressiva.This condition can be referred to by various names in clinical practice and literature,including tendon ossification,tendon mineralization,heterotopic ossification,and calcific tendonitis.The exact pathogenesis of tendon calcification remains uncertain,but current mainstream research suggests that calcification is mostly cell mediated.To further elucidate the pathogenesis of tendon calcification and to better simulate the overall process,selecting appropriate experimental animal models is important.Numerous animal models have been utilized in various clinical studies,each with its own set of advantages and limitations.In this review,we have discussed the advancements made in research on animal models of tendon calcification,with a focus on the selection of experimental animals,the sites of injury in these models,and the methods employed for modeling.
基金项目
Science and Technology Innovation Cooperation Special Programme of Sichuan Province(2022YFS0609-C1)
Industry-University-Research Cooperation Foundation(2021CXYZ01)
Luzhou Science and Technology Plan Project(2021-SYF-25)
China Postdoctoral Science Foundation(2023M732927)
Scientific Research Project of Southwest Medical University(2021ZKMS051)
Scientific Research Project of Southwest Medical University(2022QN018)
维普
万方数据