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基于光谱技术揭示中药成分与药效之间的关联机制

The correlation mechanism between traditional Chinese medicine ingredients and efficacy is revealed based on spectral technology

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本文通过系统地探讨光谱技术的原理与应用,深入剖析中药成分的光谱特性,进而阐明药效与光谱数据之间的关联模式,以期提升中药质量控制和药效评价的精准度.通过对比分析,阐明了不同光谱技术在解析中药复杂成分结构和动态变化方面的优劣.在中药药效与光谱数据的关联分析中,构建了多元统计模型,如主成分分析、偏最小二乘回归等,用于解析光谱特征与药效活性之间的定量关系,以期使光谱技术更好地服务于中药现代化,推动中药药效物质基础和作用机制的深入研究,为中药的新药开发和临床应用提供更有力的技术支持.
This paper systematically explores the principles and applications of spectroscopic technology,deeply analyzes the spectral characteristics of traditional Chinese medicine ingredients,and then clarifies the correlation model between medicinal efficacy and spectral data,in order to improve the accuracy of traditional Chinese medicine quality control and efficacy evaluation.Through comparative analysis,the advantages and disadvantages of different spectral technologies in analyzing the structure and dynamic changes of complex components of traditional Chinese medicine were clarified.In the correlation analysis of traditional Chinese medicine efficacy and spectral data,multivariate statistical models,such as principal component analysis,partial least squares regression,etc.,were constructed to analyze the quantitative relationship between spectral characteristics and pharmacodynamic activity.It is hoped that spectroscopic technology can better serve the modernization of traditional Chinese medicine,promote in-depth research on the material basis and mechanism of Chinese medicine efficacy,and provide stronger technical support for the development and clinical application of new traditional Chinese medicine.

spectral technologytraditional Chinese medicine ingredientsdrug effect correlationresearch progressdata analysis

赵天奇

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河南医药健康技师学院,河南 开封 475000

光谱技术 中药成分 药效关联 研究进展 数据分析

2024

灯与照明
重庆照明学会 重庆灯泡工业公司

灯与照明

影响因子:0.359
ISSN:1008-5521
年,卷(期):2024.48(4)