In this paper,a liquid metal microsphere was prepared.The microstructure and intravascular embolization effect of the liquid metal microsphere were investigated.The result showed that it had a spherical morphology observed by a microscope.Gallium and oxygen elements were detected by elemental analyses.Liquid metal microspheres blocked the central artery of rabbit's ear,leading to necrosis of the rabbit's ear during the embolization experiments on the rabbit's central ear artery.Blood vessels were blocked by physical embolization when the diameter of the liquid metal microspheres was comparable to that of blood vessels.Liquid metal microspheres were X-ray visible due to their high density.Pre-and post-embolization blood tests and histopathology of major organs showed that liquid metal microspheres had good biocompatibility.Therefore,liquid metal microsphere is an embolization material for great potential clinical applications.
关键词
液态金属微球/栓塞/镓/X射线可视/微观结构
Key words
liquid metal microspheres/embolization/gallium/X-ray visualization/microstructure
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