The Yajiangqiao area is located in the northeastern part of the Hunan,Guangxi and Guang-dong fold belt of in the south China fold system,northern part of the Chuankou to Mingyuefeng uplift,belongs to the important uranium-molybdenum-tungsten-tin-copper-lead-zinc metallogenic belt in eastern Hunan,its geological structure background is complex and magma activity is strong.The uranium ore-body is close to the granite body in the area,and the orebody is thicker near the rock body,its controlled by the tectonic fault zone,greisenization,hydromicatization and hematiization are close to uranium miner-alization.With the increasing difficulty of prospecting,metallogenic prediction by using geological,Geo-physical,geochemical and remote geological information,which is more and more attention has been paid to geological exploration.This paper is through the study of uranium deposit in Yajiangqiao area,is based on the extensive collection and study of predecessors works,Combined with the 1∶10,000 total gamma measurements carried out in the key locations,analysis and research the diversified information of geolo-gy,geophysical,geochemical multiple information in the region,points out the U-210Po-yeU and combi-natorial anomalies is a geochemistry indicator of favorable mineralization in the area,the spatial overlap of 210 Po and gamma-ray spectroscopic uranium halo is a favorable site for uranium mineralization.