Bone defects caused by bone diseases are a very challenging issue in modern medicine.Both pathologi-cal changes in normal bone tissue and physical damage caused by external factors can lead to difficult-to-heal bone defects.The complex microenvironment of the bone defect site makes treatment conditions more demanding.Con-structing scaffolds for bone defects is an important direction in bone tissue engineering technology and a crucial means to solve the problem of bone defect diseases.This article briefly introduces the preparation principles and methods of hydroxyapatite/graphene oxide(HA/GO)composite materials.HA/GO has no apparent toxicity to bone cells,and its rough surface structure is more conducive to the proliferation and differentiation of bone cells.Based on this,the construction methods and performance of HA/GO composite scaffolds for treating bone defect diseases are described in detail.Finally,the development prospects and challenges of HA/GO composite scaffolds in the treatment of bone diseases are discussed.
NETL
NSTL
万方数据
维普
