单宁酸包裹的阿维菌素/介孔SiO2纳米载药系统的构建与性能
Preparation and properties of tannic acid coated abamectin/mesoporous silica nano-pesticide delivery system
徐鹏 1戴伟 1曹蓉 2石伟山 3邢刚 3王钊贵 4王莎莎 1李群 1游朝群 1郝德君4
作者信息
- 1. 南京林业大学 化学工程学院,南京 210037
- 2. 南京市六合区农业技术推广中心 森林植物检疫站,南京 211500
- 3. 江苏艾津作物科技集团有限公司,南京 211511
- 4. 南京林业大学 林学院,南京 210037
- 折叠
摘要
增加农药在靶标作物叶面的滞留时间对提高农药利用率和降低农药对环境的影响具有重要意义.本文以阿维菌素(Aba)为模型药物,以单宁酸(TA)包裹的介孔SiO2 纳米颗粒为载体材料构建纳米农药载药系统,在对纳米农药载药系统结构和形貌进行表征的基础上,通过模拟释放实验、植物叶面接触角和滞留量的比较及抗紫外光解实验深入研究纳米载药系统的释放性能和叶面粘附性能.研究发现,单宁酸包覆的阿维菌素/介孔SiO2 纳米载药系统(Aba/MSNs@TA)的载药量达到 23.50％,单宁酸的包覆明显提高了载药系统在绿萝、玉米和马尾松叶面上的润湿性,叶面滞留量相较于Aba/MSNs提高了 23.4％.Aba/MSNs@TA表现出明显的pH响应性释放性能,较低的pH值环境加速了Aba的释放速度.此外,单宁酸的包覆进一步提高了载药系统中药物的抗紫外光解性能.
Abstract
It is important to increase the retention time of pesticides on the leaf surface of target crops for improv-ing pesticide utilization and reducing the impact of pesticides on the environment.In this paper,we used abamectin(Aba)as a model pesticide and mesoporous silica nanoparticles coated with tannic acid(TA)as a carrier material to construct a nano-pesticide delivery system.Based on the structural and morphological characterization of the nano-pesticide delivery system,we investigated the release performance and foliar adhesion of the nano-pesticide delivery system through simulated release experiments,comparison of contact angle and retention amount on plant foliage and UV photolysis resistance experiments.It is found that tannic acid-coated abamectin-loaded mesoporous silica nanospheres(Aba/MSNs@TA)significantly improve drug wettability on the foliage of Epi-premnum aureum,corn and masson pine,and foliar retention is also improved compared to Aba/MSNs.Aba/MSNs@TA exhibits significant pH-responsive release performance,with lower pH environments accelerating the release rate of Aba.In addition,the coating of tannic acid further improves the UV photolytic resistance of the drug in the drug-loaded system.
关键词
阿维菌素/粘附性/介孔SiO2/刺激响应/抗光降解/单宁酸/农药载药系统Key words
abamectin/adhesion/mesoporous SiO2/stimulus response/anti-photodegradation/tannic acid/pesticide delivery system引用本文复制引用
基金项目
江苏省林业科技创新与推广项目(LYKJ-南京[2022]02)
出版年
2024
NETL
NSTL
万方数据