首页|MXene基复合水凝胶在修复感染创面中的研究进展

MXene基复合水凝胶在修复感染创面中的研究进展

MXene and its composite hydrogel application in infective wound healing

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感染创面严重危害着人类的生活质量甚至是生命健康,因此研发高效且副作用小的抗菌生物材料用于修复感染创面具有广阔的市场前景.二维过渡金属碳化物(MXene)是一种新型的二维片状材料,具有优异的抗菌性能,其抗菌机制主要包括物理捕获理论、红外热效应、活性氧(ROS)生成理论、胞间分子泄露理论等,因此MXene有望成为一种更安全、有效、广谱的抗菌手段.通过水凝胶包裹MXene制成的MXene复合水凝胶比单纯水凝胶具有更佳的抗菌、抗氧化性以及光热效应等优势.本文综述了MXene的抗菌机制,并就近年来报道的MXene复合水凝胶修复感染创面的研究进行全面综述和总结.
Infected wounds seriously endanger the quality of life and even life and health of human beings,so the development of antimicrobial biomaterials with high efficiency and few side effects for the repair of infected wounds has broad market prospects.Two-dimensional transition metal carbide(MXene)is a new type of two-di-mensional sheet material with excellent antibacterial properties,and its antibacterial mechanism mainly includes physical capture theory,infrared thermal effect,reactive oxygen species(ROS)generation theory,intercellular molecular leakage theory,etc.,so MXene is expected to become a safer,effective and broad-spectrum antibacterial method.Compared with simple hydrogels,MXene composite hydrogels made of hydrogels encapsulated with MXene have better antibacterial,antioxidant properties and photothermal effects.In this paper,the antimicrobial mechanism of MXene was reviewed,and the researches on the repair of infected wounds by MXene composite hydrogels were comprehensively reviewed and summarized in recent years.

MXenecomposite hydrogelantibacterialwound repairapplication

吴晓娜、汪宜宇、赵凯

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黑龙江大学 生命科学学院,农业微生物技术教育部工程研究中心,黑龙江省寒区植物基因与生物发酵重点实验室,哈尔滨 150080

台州学院 生命科学学院,浙江省植物进化生态学与保护重点实验室,台州市生物医药与高端剂型重点实验室,台州 318000

MXene 复合水凝胶 抗菌 创面修复 应用

国家自然科学基金

32170844

2024

复合材料学报
北京航空航天大学 中国复合材料学会

复合材料学报

CSTPCD北大核心
影响因子:0.933
ISSN:1000-3851
年,卷(期):2024.41(7)