Intelligent systems are systems automate complex work with computer technology and some other technologies(such as com-munication and information technology and sensor technology).Application of intelligent systems is modern and advanced to ensure the stability of the animal laboratory environment and thus guarantee the safety of experimental animals,experimental quality and labora-tory safety.This article discuss 8 basic requirements for the design of intelligent systems for animal laboratories,especially those al-ready realized in animal laboratory that the author has participated in building,to provide experiences for later designers.