腹腔镜外科杂志2024,Vol.29Issue(1) :18-21,31.DOI:10.13499/j.cnki.fqjwkzz.2024.01.018

吲哚菁绿标记近红外荧光腹腔镜胃癌根治术的应用研究

Near infrared fluorescence-guided laparoscopic radical gastrectomy:new strategies for the use of indocyanine green

刘选文 高峰 朱甲明
腹腔镜外科杂志2024,Vol.29Issue(1) :18-21,31.DOI:10.13499/j.cnki.fqjwkzz.2024.01.018

吲哚菁绿标记近红外荧光腹腔镜胃癌根治术的应用研究

Near infrared fluorescence-guided laparoscopic radical gastrectomy:new strategies for the use of indocyanine green

刘选文 1高峰 1朱甲明2
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作者信息

  • 1. 吉林市中心医院胃肠外科,吉林 吉林,132062
  • 2. 中国医科大学附属第一医院肿瘤外科
  • 折叠

摘要

目的:探讨吲哚菁绿(ICG)在腹腔镜胃癌根治术中淋巴结定位及清扫的应用价值.方法:回顾分析2018 年1 月至2019 年5 月接受腹腔镜胃癌D2 根治术的 73 例胃癌患者的临床资料.其中 35 例术前经ICG标记后行腹腔镜手术(ICG组),38 例行常规腹腔镜胃癌根治术(对照组).对比分析两组淋巴结清扫总数、手术时间、出血量、术后并发症及住院时间.结果:两组均顺利完成腹腔镜胃癌根治术.ICG组与对照组手术时间[(195.31±35.12)min vs.(201.48±36.57)min,P>0.05]、术中出血量[(90.58±18.27)mL vs.(92.44±20.25)mL,P>0.05]、术后排气时间[(3.25±1.35)d vs.(3.17±1.65)d,P>0.05]、术后住院时间[(12.55±3.25)d vs.(13.50±3.65)d,P>0.05]差异均无统计学意义.两组淋巴结清扫数量差异有统计学意义[(47.71±16.43)枚vs.(30.22±11.67)枚,P<0.05].术后平均随访(27±13)个月,其中 2 例吻合口复发,予以手术切除,无死亡病例.结论:ICG成像技术方便、安全、有效,可确保淋巴结清扫的安全性、有效性,避免淋巴结残留.

Abstract

Objective:To assess the use of indocyanine green(ICG)during laparoscopic radical gastrectomy for lymph node location and dissection.Methods:Retrospective analysis was done on the clinical data of 73 gastric cancer patients who underwent lapa-roscopic D2 radical gastrectomy between Jan.2018 and May 2019.The ICG group,which consisted of 35 patients,received laparoscopic surgery after ICG labeling,while the control group consisted of 38 patients,underwent traditional laparoscopic radical gastrectomy.Between the two groups,comparisons and analyses were made regarding the total number of lymph node dissections,operation time,blood loss,postoperative complications and hospital stay.Results:Both groups successfully completed laparoscopic radical gastric cancer surgery,no case was converted to laparotomy.In the ICG group and control group,the operative time[(195.31±35.12)min vs.(201.48±36.57)min,P>0.05],the intraoperative blood loss[(90.58±18.27)mL vs.(92.44±20.25)mL],the postoperative exhaust time[(3.25±1.35)d vs.(3.17±1.65)d,P>0.05],and the postoperative hospitalization time[(12.55±3.25)d vs.(13.50±3.65)d,P>0.05]were not statistically significantly different.The number of lymph node dissection in both groups was statistically significant different[(47.71±16.43)vs.(30.22±11.67),P<0.05].The follow-up period was(27±13)months,and two cases of anastomotic recurrence were treated with surgical resection without death.Conclusions:ICG imaging technology is convenient,safe and effective.This technology may become a criterion for lymph node dissection in the future,and it can ensure the safety and effectiveness of lymph node dissection to avoid lymph node residue.

关键词

胃肿瘤/胃癌根治术/腹腔镜检查/吲哚菁绿/示踪剂

Key words

Stomach neoplasms/Radical gastrectomy for cancer/Laparoscopy/Indocyanine green/Tracer

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出版年

2024
腹腔镜外科杂志
山东大学

腹腔镜外科杂志

CSTPCD
影响因子:0.861
ISSN:1009-6612
参考文献量20
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