吲哚菁绿荧光显影在腹腔镜再次胆道探查术中的应用研究
Application of indocyanine green fluorescence imaging in laparoscopic biliary re-exploration
朱超 1刘会春 1王勇 1庞青 1潘洪涛 1胡小四 1陈石磊 1周帅 1王志成 1金浩1
作者信息
- 1. 安徽省第二人民医院肝胆胰外科,安徽 合肥,230011
- 折叠
摘要
目的:探讨吲哚菁绿荧光显影在腹腔镜再次胆道探查术中的应用价值.方法:回顾分析2020 年1 月至2022 年12 月行腹腔镜再次胆道探查术的52 例患者的临床资料,其中24 例行荧光腹腔镜手术(荧光组),28 例行普通腹腔镜手术(常规组),对比两组手术相关指标.结果:两组患者基线资料、术中联合胆肠内引流、术后胆漏发生率、结石残留率差异无统计学意义(P＞0.05).荧光组与常规组手术时间[(119.2±44.0)min vs.(159.0±52.4)min]、寻找肝外胆管时间[(21.0±7.8)min vs.(38.8±12.5)min]、出血量[(97.1±61.3)mL vs.(226.8±210.2)mL]、术后感染率(8.3%vs.32.1%)、胰腺炎发生率(4.2%vs.28.6%)、术后拔除引流管时间[(2.7±1.1)d vs.(3.8±1.4)d]、术后住院时间[(6.4±2.3)d vs.(10.3±3.2)d]差异均有统计学意义(P＜0.05).结论:腹腔镜再次胆道探查术中应用吲哚菁绿荧光显影是安全、有效的,可缩短手术时间,降低术后并发症发生率,值得进一步推广应用.
Abstract
Objective:To evaluate the clinical application value of indocyanine green fluorescence imaging in laparoscopic bili-ary re-exploration.Methods:Retrospective analysis was performed on the clinical data of 52 patients who underwent laparoscopic biliary re-exploration from Jan.2020 to Dec.2022.The clinical indexes related to 24 cases of fluorescence laparoscopy(fluorescence group)and 28 cases of ordinary laparoscopy(ordinary group)were compared.Results:There were no significant differences in baseline data,intraoperative combined biliary enteral drainage,postoperative biliary leakage,and calculi residual rates between the two groups(P＞0.05).Operation time[(119.2±44.0)min vs.(159.0±52.4)min],extrahepatic bile duct search time[(21.0±7.8)min vs.(38.8±12.5)min],blood loss[(97.1±61.3)mL vs.(226.8±210.2)mL],the incidence of postoperative infection(8.3%vs.32.1%),the incidence of pancreatitis(4.2%vs.28.6%),postoperative drainage tube removal time[(2.7±1.1)d vs.(3.8±1.4)d],and post-operative hospitalization time[(6.4±2.3)d vs.(10.3±3.2)d]in fluorescence group and ordinary group were statistically significantly different(P＜0.05).Conclusions:Indocyanine green fluorescence imaging is safe and effective in laparoscopic biliary re-exploration,which can shorten the operation time and reduce the incidence of postoperative complications.This technique is worthy of further appli-cation and promotion in clinical practice.
关键词
胆道探查术/腹腔镜检查/吲哚菁绿/荧光成像技术Key words
Biliary exploration/Laparoscopy/Indocyanine green/Fluorescence imaging technology引用本文复制引用
基金项目
安徽省高校自然科学研究项目(2023AH053366)
安徽省高校自然科学研究项目(2023AH053384)
出版年
2024
国家科技期刊平台
NSTL
万方数据