Objective:To summarize and discuss the clinical features,diagnosis and treatment of intrahepatic biliary cystadeno-carcinoma.Methods:The general clinical data,imaging findings,laboratory results,surgical methods and prognosis of 28 patients with intrahepatic biliary cystadenocarcinoma confirmed by pathology from Jan.2001 to Dec.2022 were retrospectively analyzed.After admis-sion,patients underwent total abdominal enhanced CT or upper abdominal enhanced magnetic resonance examination.16 patients had no clinical symptoms,9 patients suffered from upper abdominal distension and pain,and 3 patients presented with skin and sclera yellow-ing.Results:Nine cases were diagnosed as intrahepatic biliary cystadenocarcinoma by preoperative imaging examination.CA19-9 ele-vated in 15 patients,and CA125 increased in 5 patients,while AFP was normal in all patients.In 28 patients,local tumor resection was performed in 8 cases,left lateral hepatic lobectomy was performed in 6 cases,left hemihepatectomy was performed in 9 cases,and right hemihepatectomy in5 cases.The operation time was(205.8±30.8)min,the intraoperative blood loss was(210.8±45.2)mL,and the average postoperative hospital stay was(7.6±2.1)d.Five cases of postoperative bile leakage occurred and improved after conservative treatment.Postoperative follow-up ranged from 5 to 100 months,19 patients experienced recurrence and 6 patients died.Conclusions:According to laboratory examination and imaging findings,intrahepatic biliary cystadenocarcinoma is difficult to be diagnosed before operation.Radical resection is the main treatment method,and regular follow-up is required after operation.
关键词
肝肿瘤/胆管囊腺癌/肝切除术/诊断/治疗
Key words
Liver neoplasms/Cystadenocarcinoma of bile duct/Hepatectomy/Diagnosis/Therapy
维普
万方数据