腹腔镜外科杂志2024,Vol.29Issue(6) :451-456.DOI:10.13499/j.cnki.fqjwkzz.2024.06.451

老年腹股沟疝术后并发症风险列线图预测模型的建立及验证

Construction and verification of the nomogram prediction model for postoperative complications of elderly patients with inguinal hernia

张天昊 郝志伟 安杰 李金 李锦行 姜战武
腹腔镜外科杂志2024,Vol.29Issue(6) :451-456.DOI:10.13499/j.cnki.fqjwkzz.2024.06.451

老年腹股沟疝术后并发症风险列线图预测模型的建立及验证

Construction and verification of the nomogram prediction model for postoperative complications of elderly patients with inguinal hernia

张天昊 1郝志伟 1安杰 1李金 1李锦行 2姜战武1
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作者信息

  • 1. 保定市第一中心医院普通外二科,河北 保定,071000
  • 2. 保定市第一中心医院产科
  • 折叠

摘要

目的:建立老年腹股沟疝患者行腹腔镜经腹腹膜前疝修补术后并发症发生的列线图预测模型.方法:回顾分析2021 年1 月至2023 年1 月为254 例老年腹股沟疝患者行腹腔镜经腹腹膜前疝修补术的围手术期资料,术后至少随访6 个月,采用二元Logistic回归分析探讨独立危险因素.再以独立危险因素构建可视化列线图模型,利用受试者工作特征曲线评价模型区分度、校准图评估模型校准度,绘制临床决策曲线分析临床获益能力.结果:254 例患者均获得随访,其中33 例发生并发症,发生率为12.99%.单因素分析结果显示,BMI、疝囊直径、难复性疝、疝环粘连程度、术中出血量与术后并发症相关(P<0.05).二元Logistic回归分析显示,BMI>24 kg/m2、疝囊直径>5 cm、难复性疝、疝环重度粘连、术中出血量>10 mL是术后并发症的独立危险因素.构建列线图预测模型,受试者工作特征曲线下面积为 0.845,95%可信区间 0.781~0.910,约登指数0.755,敏感度为0.879,特异度0.876,模型具有较高的预测价值.校正曲线显示预测值靠近理想曲线,一致性较好,在临床决策曲线中该模型的临床效能表现良好.结论:根据危险因素构建的列线图预测模型具有较高的区分度与校准度,有助于临床医生术前评估及术中操作,以尽早对高危患者进行预防与治疗.

Abstract

Objective:To construct a nomogram prediction model for complications after laparoscopic transabdominal preperito-neal(TAPP)hernia repair in elderly patients with inguinal hernia.Methods:The perioperative data of 254 elderly patients with ingui-nal hernia who underwent TAPP from Jan.2021 to Jan.2023 were retrospectively analyzed,and the patients were followed up for at least 6 months.Binary logistic regression analysis was used to explore the independent risk factors,by which visual nomogram model was con-structed.Receiver operating characteristic curve was used to evaluate the discrimination of the model,calibration chart was used to eva-luate the calibration of the model,and the clinical decision curve was drawn to analyze the clinical ability of obtaining benefit.Results:All254 patients were followedup,andcomplicationsoccurredin33 patients,withanincidenceof12.99%.Univariateanalysisshowed that BMI,diameter of hernia sac,irreducible hernia,degree of hernia ring adhesion and intraoperative blood loss were associated with postoperative complications(P<0.05).Binary logistic regression analysis showed that BMI>24 kg/m2,hernia sac diameter>5 cm,irreducible hernia,severe adhesion of hernia ring,and intraoperative blood loss>10 mL were independent risk factors for postoperative complications.The nomogram prediction model was constructed,the area under the receiver operating characteristic curve was 0.845,95%CI=0.781~0.910,Youden index was 0.755,sensitivity was 0.879,specificity was 0.876,the model had high predictive value.The calibration curve showed that the predictive value was close to the ideal curve,and there was good consistency.The clinical decision curve showed that the model had good clinical efficacy.Conclusions:The nomogram prediction model constructed by risk factors has high discrimination and calibration,which is helpful for clinicians in preoperative evaluation and intraoperative operation,so as to pre-vent and treat high-risk patients as soon as possible.

关键词

疝,腹股沟/腹腔镜检查/老年人/手术后并发症/危险因素/列线图/预测模型

Key words

Hernia,inguinal/Laparoscopy/Aged/Postoperative complications/Risk factors/Nomograms/Prediction model

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基金项目

河北省保定市科技计划项目(2141ZF076)

出版年

2024
腹腔镜外科杂志
山东大学

腹腔镜外科杂志

CSTPCD
影响因子:0.861
ISSN:1009-6612
参考文献量16
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