吲哚菁绿荧光显像技术在充满型胆囊结石腹腔镜胆囊切除术中的临床应用
The clinical application of indocyanine green fluorescence imaging technology in laparoscopic cholecystectomy for filled type cholecystolithiasis
王佳杰 1李文波 1李良 1鲁俊 1张军1
作者信息
- 1. 蚌埠医科大学附属合肥市第二人民医院 合肥市第二人民医院普通外科,安徽 合肥,230011
- 折叠
摘要
目的:探讨吲哚菁绿荧光显像技术在充满型胆囊结石腹腔镜胆囊切除术(LC)中的安全性及有效性.方法:选取2023 年1 月至2023 年10 月收治的76 例需行LC的充满型胆囊结石患者,按随机数表法分为荧光组(n=36)与常规组(n=40),对比分析两组术中情况、术后相关指标及并发症情况.结果:与常规组相比,荧光组手术时间、游离胆囊三角与离断胆囊管时间、术中出血量、逆行切除胆囊例数、胆囊破裂例数均少于常规组,差异有统计学意义(P<0.05);两组术中放置引流管例数差异无统计学意义(P>0.05).两组术后第3 天白细胞计数、丙氨酸转氨酶水平、直接胆红素水平及术后住院时间、术后疼痛数字评分差异亦无统计学意义(P>0.05).两组术后腹腔出血、胆漏、胆管损伤情况差异无统计学意义(P>0.05).术后1～3 个月随访,复查无异常.结论:充满型胆囊结石行LC术中应用吲哚菁绿荧光显像技术是安全、有效、便捷的,值得推广应用.
Abstract
Objective:To investigate the safety and effectiveness of indocyanine green fluorescence visualization technique in laparoscopic cholecystectomy(LC)for filled type cholecystolithiasis.Methods:Seventy-six patients with filled type cholecystolithiasis requiring LC admitted from Jan.2023 to Oct.2023 were selected and divided into fluorescence group(n=36)and conventional group(n=40)according to the random number table method,in order to compare and analyze intraoperative conditions,postoperative related indexes,and complications in the two groups.Results:Compared with the conventional group,the fluorescence group showed significant reduction in operation time,time to separate the Calot triangle and transect the cystic duct,intraoperative blood loss,number of retro-grade LC,and cases of gallbladder rupture(P<0.05).There was no statistically significant difference in the number of drainage tube placement between the two groups(P>0.05).Postoperative indicators,including white blood cell count,alanine aminotransferase level and direct bilirubin level on the postoperative third day,hospital stay,and pain numerical rating scores,showed no statistically signifi-cant difference(P>0.05).Regarding the postoperative complications,there was no statistically significant difference in the number of intra-abdominal hemorrhage,bile leakage,or bile duct injury between the two groups(P>0.05).There was no abnormality in the post-operative follow-up of 1-3 months.Conclusions:The application of indocyanine green fluorescence imaging technology in LC for filled type cholecystolithiasis is safe,effective,and convenient,and is worth popularization and application.
关键词
充满型胆囊结石/吲哚菁绿/胆囊切除术,腹腔镜Key words
Filled cholecystolithiasis/Indocyanine green/Cholecystectomy,laparoscopic引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据