腹腔镜外科杂志2024,Vol.29Issue(9) :683-687.DOI:10.13499/j.cnki.fqjwkzz.2024.09.683

经鼻胆管吲哚菁绿导航在老年胆管结石患者序贯治疗中的应用

The application of transnasal bile duct indocyanine green navigation in sequential treatment of cholangiolithiasis in elderly patients

蔡小丹 冯伟 马垚 汪启乐 陈思颖 刘加宁
腹腔镜外科杂志2024,Vol.29Issue(9) :683-687.DOI:10.13499/j.cnki.fqjwkzz.2024.09.683

经鼻胆管吲哚菁绿导航在老年胆管结石患者序贯治疗中的应用

The application of transnasal bile duct indocyanine green navigation in sequential treatment of cholangiolithiasis in elderly patients

蔡小丹 1冯伟 2马垚 2汪启乐 2陈思颖 2刘加宁3
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作者信息

  • 1. 江苏省人民医院宿迁医院普外科,江苏 宿迁,223800
  • 2. 徐州医科大学附属宿迁医院肝胆胰外科
  • 3. 徐州医科大学附属宿迁医院消化内科
  • 折叠

摘要

目的:探讨经鼻胆管吲哚菁绿导航在内镜十二指肠乳头括约肌小切开联合球囊扩张术(ESBD)后序贯行腹腔镜胆囊切除术(LC)治疗老年胆管结石患者中的应用价值.方法:选取2020 年1 月至2023 年1 月收治的胆囊结石伴胆总管结石的60 例老年患者,采用ESBD序贯LC的治疗方案,根据LC术中是否经鼻胆管注射吲哚菁绿行术中导航分为常规组(n=30)与导航组(n=30),对比分析两组患者临床资料.结果:两组一般资料差异无统计学意义,均成功完成ESBD序贯LC,导航组术中证实肝门区胆管分型异常 2 例,无中转开腹、胆管损伤.常规组与导航组手术时间[(68.43±27.40)min vs.(63.17±23.25)min]、术中出血量[(12.37±5.53)mL vs.(11.03±4.66)mL]、LC术后住院时间[(4.90±0.99)d vs.(4.77±0.94)d]差异无统计学意义(P>0.05),术后鼻胆管造影胆囊管残端长度[(10.67±2.61)mm vs.(5.87±2.47)mm]差异有统计学意义(P<0.01).结论:术中经鼻胆管推注吲哚菁绿较常规静脉推注具有无背景干扰的优势,能更清晰地显示肝门胆管关系,确认胆道异常分型,减少胆囊管残端残留过长引起的术后不适,对于提高老年患者ESBD术后序贯LC的安全性具有积极作用.

Abstract

Objective:To investigate the application value of transnasal biliary tract indocyanine green(ICG)navigation in sequential laparoscopic cholecystectomy(LC)after endoscopic duodenal papillary sphincter subtotal incision balloon dilatation(ES-BD)in the treatment of elderly patients with bile duct calculi.Methods:Sixty elderly patients with cholecystolithiasis accompanied by choledocholithiasis admitted from Jan.2020 to Jan.2023 were selected to adopt the treatment plan of sequential LC with ESBD,and they were divided into the conventional group(n=30)and the navigation group(n=30)according to whether or not ICG was injected via the nasobiliary duct for intraoperative navigation during LC,and the relevant clinical data were collected and statistically analyzed.Results:There was no significant difference in the general information of patients in the two groups,and ESBD sequential LC was su-ccessfully performed for all patients.Two cases of abnormal bile duct type in the hepatoportal area were confirmed intraoperatively in the navigation group,and there was no intraoperative conversion to laparotomy and no bile duct injury.Surgical time[(68.43±27.40)min vs.(63.17±23.25)min],intraoperative blood loss[(12.37±5.53)mL vs.(11.03±4.66)mL]and postoperative hospital stay[(4.90±0.99)d vs.(4.77±0.94)d]after LC in the conventional group and navigation group were not significantly different(P>0.05).Postoperative cystic duct stump length found by nasal cholangiography[(10.67±2.61)mm vs.(5.87±2.47)mm]was signifi-cantly different(P<0.01).Conclusions:Intraoperative navigation using ICG injection through transnasal bile duct has the advantage of no background interference over conventional intravenous injection ICG,it can more clearly show the relationship between the hepatopor-tal bile ducts and confirm the biliary abnormalities type,and it can reduce the postoperative discomfort caused by the excessive length of cystic duct stump,which is of positive clinical significance in improving the safety of sequential LC after ESBD in elderly patients.

关键词

胆管结石/吲哚菁绿/内镜十二指肠乳头括约肌小切开球囊扩张术/胆囊切除术,腹腔镜/老年人

Key words

Cholangiolithiasis/Indocyanine green/Endoscopic small incision and balloon dilatation of papillary sphincter/Cholecystectomy,laparoscopic/Aged

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基金项目

宿迁市重点社会发展项目(S202317)

宿迁市重点社会发展项目(S201717)

江苏省卫健委医学科研项目(Z202317)

宿迁市科技计划项目(Z2022055)

出版年

2024
腹腔镜外科杂志
山东大学

腹腔镜外科杂志

CSTPCD
影响因子:0.861
ISSN:1009-6612
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