Research on the TCM Syndrome Types and the Distribution Patterns of Syndrome Elements of Primary Osteoporosis Based on Literature Study
Objective:To explore the TCM syndromes and the distribution patterns of syndrome elements in patients with primary osteoporosis.Methods:Relevant literature on the TCM syndrome types of primary osteoporosis was retrieved from the databases CNKI and Wanfang(the retrieval time was from the establishment of the databases to May 2023).Excel tables were used to extract the TCM syndrome type information of different patients with primary osteoporosis.The names of the syndrome types in the literature were standardized,syndrome elements were extracted from the TCM syndrome types,a database was established,and frequency analysis was performed using software SPSS 27.0.1 respectively.Results:A total of 79 eligible literatures were included,with 18 251 cases.After standardization,a total of 41 TCM syndrome types and 16 syndrome elements were included,including 4 disease location syndrome elements and 12 disease nature syndrome elements.Among the total syndrome type distribution,there were 8 syndrome types with a frequency more than 3%.Among them,the liver-kidney yin deficiency syndrome ranked first,with 4017 cases(22.05%),followed by the spleen-kidney yang deficiency syndrome with 3236 cases(17.77%),the qi stagnation and blood stasis syndrome with 1733 cases(9.51%),the kidney yang deficiency syndrome with 1631 cases(8.95%),the kidney deficiency and blood stasis syndrome with 1433 cases(7.87%),the spleen-kidney deficiency syndrome with 1087 cases(5.97%),the qi deficiency and blood stasis syndrome with 594 cases(3.26%),and the spleen-kidney qi deficiency syndrome with 549 cases(3.01%).Among the total syndrome element distribution,the disease location syndrome elements were the kidney in 13 700 cases(56.00%),the spleen in 5720 cases(23.26%),the liver in 4454 cases(18.11%),and the stomach in 646 cases(2.63%);the disease nature syndrome elements were yang deficiency in 5301 cases(27.92%),yin deficiency in 4851 cases(25.55%),blood stasis in 4139 cases(21.80%),qi stagnation in 1759 cases(9.26%),qi deficiency in 1700 cases(8.95%),essence deficiency in 606 cases(3.19%),and the frequencies of the other 6 disease nature syndrome elements were low(all frequencies less than 3.00%).Conclusion:The disease locations of primary osteoporosis are mainly distributed in the kidney,spleen,liver,and stomach.The distribution of syndrome elements is a mixture of deficiency and excess.The deficiency syndromes are mainly yang deficiency,yin deficiency,and qi deficiency,while the excess syndromes are mainly blood stasis and qi stagnation.The most common TCM syndrome types are the liver-kidney yin deficiency syndrome,the spleen-kidney yang deficiency syndrome,the qi stagnation and blood stasis syndrome,and the kidney yang deficiency syndrome.The pathogenesis and syndromes of primary osteoporosis are complex and diverse,and TCM syndrome types sometimes cannot fully reflect the specific situation of patients.The reasonable combination of syndrome elements can effectively deal with the complex pathogenesis and syndromes.
primary osteoporosisTCM syndrome typessyndrome elementdisease locationdisease natureliterature study
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