Research progress of cell senescence in the occurrence and development of radiation injury
Radiation injury is a common complication of radiotherapy for cancer patients.Radiation injury has a relative high incidence and is difficult to prevent and to be treated,which may seriously affects the life quali-ty of patients.Cell senescence is a state in which the cell cycle is stagnated,and radiation therapy usually makes cells enter a state of senescence,which facilitates the removal of tumor cells in the body while may also causing damage to normal cells.With the progress of research,the role of ionizing radiation-induced cell se-nescence in radiation injury has received more and more attention,and the research progress of cell senes-cence in radiation injury is reviewed in this paper.