首页|细胞衰老在放射损伤发生发展中的研究进展

细胞衰老在放射损伤发生发展中的研究进展

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放射损伤是肿瘤患者放射治疗的常见并发症,其发生率高,防治困难,严重影响患者的生活质量.细胞衰老是一种细胞周期停滞的状态,放射治疗通常会促使受照射细胞进入衰老状态,这有利于体内肿瘤细胞的清除,同时也对正常细胞产生伤害.随着研究的不断深入,电离辐射诱导的细胞衰老在放射损伤中发挥的作用越来越受到重视,本文对细胞衰老在放射损伤中的研究进展进行综述.
Research progress of cell senescence in the occurrence and development of radiation injury
Radiation injury is a common complication of radiotherapy for cancer patients.Radiation injury has a relative high incidence and is difficult to prevent and to be treated,which may seriously affects the life quali-ty of patients.Cell senescence is a state in which the cell cycle is stagnated,and radiation therapy usually makes cells enter a state of senescence,which facilitates the removal of tumor cells in the body while may also causing damage to normal cells.With the progress of research,the role of ionizing radiation-induced cell se-nescence in radiation injury has received more and more attention,and the research progress of cell senes-cence in radiation injury is reviewed in this paper.

cell senescenceionizing radiationradiation injury

牛晓凤、杨思瑜、邓丽娟、任钲、毕承柳、杨军

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昆明医科大学第三附属医院 云南省肿瘤医院,昆明 650118

细胞衰老 电离辐射 放射损伤

2024

辐射防护通讯
中国辐射防护研究院

辐射防护通讯

影响因子:0.135
ISSN:1004-6356
年,卷(期):2024.44(6)