Effect of Shenqi Maiwei Dihuang Decoction and Metformin on Glucose Metabolism and TCM Syndrome of Type 2 Diabetes Patients with Qi Yin Deficiency Syndrome
Objective To analyze the effect of Shenqi Maiwei Dihuang Decoction combined with metformin in patients with type 2 diabetes mellitus(T2DM)with Qi-Yin deficiency syndrome.Methods 70 T2DM patients with qi and Yin deficiency syndrome admitted to the hospital from January 2020 to June 2023 were selected as the research objects.According to the random number table method,they were divided into a control group and an observation group,with 35 cases in each group.The control group was treated with metformin,and the observation group was treated with Shenqi Maiwei Dihuang decoction on the basis of the control group.The treatment lasted for 12 weeks.The clinical efficacy,TCM syndrome score,glucose metabolism index and adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 94.29%,which was higher than 77.14%of the control group,the difference was statistically significant(P＜0.05).Before treatment,there were no significant differences in the scores of dry throat,fatigue,shortness of breath,lazy speech,and five irritability,fasting blood glucose(FBG),2 h postprandial blood glucose(2 hPBG),and glycosylated hemoglobin(HbA1c)between the two groups(P＞0.05);after treatment,the score of dry throat and dry mouth in the observation group was(1.59±0.26)points,the score of tiredness and fatigue was(1.15±0.20)points,the score of shortness of breath and lazy speech was(1.36±0.19)points,and the score of five upset was(1.25±0.11)points,FBG was(6.31±0.94)mmol/L,2 hPBG was(8.15±1.21)mmol/L,HbA1c was(6.25±0.87)%.which were lower than(2.39±0.35)points,(1.66±0.31)points,(2.25±0.28)points,(2.08±0.19)points,(7.56±1.25)mmol/L,(10.39±1.54)mmol/L,(7.39±1.05)%of the control group,the differences between the two groups were statistically significant(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion Shenqi Maiwei Dihuang Decoction plus metformin can alleviate the symptoms of T2DM patients with Qi-Yin deficiency syndrome,regulate glucose metabolism,and no serious adverse reactions.
Type 2 diabetesQi and Yin deficiency syndromeShenqi Maiwei Dihuang DecoctionMetforminGlucose metabolismAdverse reactions
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