A Study on Transcranial Magnetic Stimulation Assisting Paroxetine in Promoting Rehabilitation of Elderly Depression Patients with Anxiety Symptoms
Objective To observe the effect of transcranial magnetic stimulation(TMS)assisted paroxetine on the reha-bilitation of elderly depression patients with anxiety symptoms.Methods 156 elderly patients with depression and anxiety admitted to this hospital from October 2021 to October 2022 were selected as the research objects,and they were divided into a control group and an observation group by the random number table method.The control group(n=78)was treated with conventional paroxetine,and the observation group(n=78)was treated with transcranial magnetic stimulation on the basis of the control group.The clinical efficacy,psychological state,disease recovery and sleep quality were compared between the two groups.Results The total effective rate of the observation group was 97.44％,which was higher than 88.46％ of the control group,the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in the scores of Hamilton Depression Scale(HAMD-17)and Hamilton Anxiety Scale(HAMA)between the two groups(P>0.05).After treatment,the HAMD and HAMA scores of the observation group were(6.12±1.21)points and(4.78±1.04)points,respectively,which were lower than(12.45±0.98)points and(13.78±1.12)points of the control group,the differences between the two groups were statistically significant(P<0.05).Before treatment,there were no statistically significant differences in Clinical Global Impressions severity of Illness Scale(CGI-SI)and Pittsburgh Sleep Quality Index(PSQI)scores between the two groups(P>0.05).After treatment,the CGI-SI and PSQI scores of the observation group were lower than those of the control group,and the differences between the two groups were statistically significant(P<0.05).Conclusion The application of transcranial magnetic stimulation combined with paroxetine in the treatment of elderly patients with depression and anxiety can promote the improvement of negative emotions,strengthen the quality of disease recovery and sleep quality,and promote the clinical treatment effect.
Geriatric depressionTranscranial magnetic stimulationParoxetineSymptoms of anxietyEffect of rehabilita-tion
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