Clinical Observation on the Effect of Neuroendoscopic Transfrontal Approach Hematoma Removal in Patients with Hypertensive Cerebral Hemorrhage
Objective To analyze the effect of neuroendoscopic transfrontal approach hematoma evacuation on patients with hypertensive intracerebral hemorrhage(HICH).Methods 92 patients with HICH admitted to the Sishui Contry People's Hospital from August 2021 to August 2023 were selected as the research objects.According to the random number table method,they were divided into a control group and an observation group,with 46 cases in each group.The control group underwent neuroendoscopic hematoma removal via temporal lobe approach,and the observation group underwent neuroendoscopic hematoma removal via frontal lobe approach.The clinical efficacy,perioperative indicators,neurotrophic factors,cerebral hemodynamics,and complications were compared between the two groups.Results The total effective rate and hematoma clearance rate of the observation group were 93.48%and 95.65%,which were higher than 78.26%and 80.43%of the control group,the differences were statistically significant between the two groups(P＜0.05).After operation,the levels of nerve growth factor,brain-derived neurotrophic factor,insulin-like growth factor-1 in the observation group were(149.87±14.65)pg/mL,(4.89±0.63)ng/mL and(114.83±9.20)μg/L,respectively,which were higher than(138.64±12.36)pg/mL,(4.31±0.48)ng/mL,(106.95±7.64)μg/L in the control group,and the pulsatility index was(0.70±0.11),which were lower than(0.91±0.17)in the control group,the average blood flow velocity was(69.85±7.20)cm/s in the control group,which was faster than(63.68±5.19)cm/s in the control group,and the differences between the two groups were statistically significant(P＜0.05).There was no significant difference in intraoperative blood loss,operation time,hospital stay and incidence of complications between the two groups(P＞0.05).Conclusion Endoscopic transfrontal approach hematoma evacuation can effectively remove the hematoma in patients with HICH,improve the levels of neurotrophic factors and cerebral hemodynamics,has good security.
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