Effect of Xiaoer Feike Granule and Azithromycin in the Treatment of Mycoplasma Pneumonia in Children and Its Influence on the Time of Symptom Disappearance and Inflammation
Objective To explore the effect of Xiaoer Feike Granules combined with azithromycin in the treatment of mycoplasma pneumonia in children.Methods 80 children with mycoplasma pneumonia admitted to the Central Hospital of Dongyinggang Economic Development Zone from May 2021 to May 2023 were selected as the research objects.They were divided into a control group(n=40)and an observation group(n=40)according to the random number table method.The control group was treated with azithromycin,and the observation group was treated with Xiaoar Feike Granules on the absis of the control group.The clinical efficacy,symptom disappearance time,inflammatory response,pulmonary function index and adverse reactions were compared between the two groups.Results The overall response rate of the observation group was 95.00%,which was higher than 77.50%of the control group,and the difference was statistically significant(P<0.05).The symptom disappearance time of the observation group was shorter than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of inflammatory response indexes C-reactive protein,tumor necrosis factor-α and interleukin-6 in the observation group were lower than those in the control group,and the levels of forced expiratory volume in the first second and maximum vital capacity were greater than those in the control group,the differences between the two groups were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Xiaoer Feike Granule combined with azithromycin can accelerate the disappearance of clinical symptoms of mycoplasma pneumonia in children,reduce inflammatory response,improve lung function,with high safety.
Mycoplasma pneumonia in childrenXiaoer Feike GranulesAzithromycinClinical symptomsInflammatory response
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