首页|黄体酮注射液结合地屈孕酮片治疗先兆流产的保胎效果及对症状缓解时间的影响

黄体酮注射液结合地屈孕酮片治疗先兆流产的保胎效果及对症状缓解时间的影响

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目的 探讨在先兆流产患者中使用黄体酮注射液结合地屈孕酮片治疗的效果.方法 选择 2021 年 12 月—2023 年10 月我院收治的 60 例先兆流产患者为研究对象,按随机数字表法将其分为对照组与观察组,各 30 例.对照组使用地屈孕酮片治疗,在对照组的基础上,观察组使用黄体酮注射液治疗,两组持续治疗至先兆流产症状消失.对比两组保胎效果、症状缓解时间、性激素水平、不良反应发生情况.结果 观察组的保胎成功率为 93.33%,高于对照组的73.33%,止血、腰酸、腹痛、宫缩症状的缓解时间均较对照组缩短,组间差异有统计学意义(P<0.05);治疗后,观察组雌二醇、人绒膜促性腺激素、孕酮水平均高于对照组,组间差异有统计学意义(P<0.05);两组不良反应比较,差异无统计学意义(P>0.05).结论 黄体酮注射液结合地屈孕酮片治疗先兆流产患者,可提高患者的保胎成功率,加快临床症状缓解时间,调节性激素水平,且用药安全性良好.
The Effect of Progesterone Injection Combined with Dydrogesterone Tablets in the Treatment of Threatened Abortion and Its Effect on Symptom Relief Time
Objective To investigate the effect of progesterone injection combined with dydrogesterone tablets in the treatment of threatened abortion.Methods 60 patients with threatened abortion admitted to our hospital from December 2021 to October 2023 were selected as the research objects.According to the random number table method,they were divided into a control group and an observation group,with 30 cases in each group.The control group was treated with dydrogesterone tablets,and the observation group was treated with progesterone injection on the basis of the control group.The two groups continued to be treated until the symptoms of threatened abortion disappeared.The effect of tocolysis,symptom relief time,sex hormone levels and adverse reactions were compared between the two groups.Results The success rate of tocolysis in the observation group was 93.33%,which was higher than 73.33%in the control group.The relief time of hemostatic,lumbar acid,abdominal pain and uterine contraction symptoms were shorter than those in the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of estradiol,human chorionic gonadotropin and progesterone in the observation group were higher than those in the control group,and the differences between the two groups were statistically significant(P<0.05).There was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion Progesterone injection combined with dydrogesterone tablets in the treatment of patients with threatened abortion can improve the success rate of fetal protection,accelerate the remission time of clinical symptoms,regulate the level of sex hormones,and the drug safety is good.

Threatened abortionProgesteroneDydrogesterone tabletsTocolysis effectSymptom relief timeSex hormone Levels

邓建军

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烟台业达医院产科,山东烟台 265500

先兆流产 黄体酮 地屈孕酮片 保胎效果 症状缓解时间 性激素水平

2024

反射疗法与康复医学

反射疗法与康复医学

ISSN:
年,卷(期):2024.5(4)
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