Analysis of Therapeutic Effect of Dopamine Combined with Dobutamine in Patients with Severe Pneumonia
Objective To explore the analysis of therapeutic effect of dopamine combined with dobutamine in patients with severe pneumonia.Methods 82 patients with severe pneumonia admitted to the hospital from March 2021 to April 2023 were selected as the research objects,and randomly divided into a control group and an observation group,with 41 cases each group.The control group received routine treatment,while the observation group received dopamine combined withdobutamine on the basis of the control group.Both groups received continuous treatment for one week.The blood gas analysis,inflammatory indexs,and clinical symptom relief time between the two groups were compared.Results After treatment,the blood oxygen saturation and partial pressure of oxygen in the observation group were(93.96±6.82)%and(80.86±7.33)mmHg,respectively,which were higher than(90.96±6.26)%and(72.76±6.64)mmHg in the control group,with statistical significance between the two groups(P<0.05).After treatment,the C-reactive protein,tumor necrosis factor-α and interleukin-6 in the observation group were(55.66±4.08)ng/mL,(167.11±14.28)pg/mL,and(75.36±6.33)pg/mL,respectively,which were lower than(73.26±5.70)ng/mL,(225.26±15.33)pg/mL and(92.63±8.47)pg/mL in the control group,with statistical significance between the two groups(P<0.05).The time for fever relief,cough resolution,and lung rale disappearance in the observation group were(4.49±0.85)d,(7.24±1.02)d and(7.72±1.36)d,respectively,which were shorter than(6.67±1.02)d,(10.12±1.56)d and(10.19±1.50)d in the control group,with statistical significance between the two groups(P<0.05).Conclusion The combination of dopamine and dobutamine has a good curative effect in severe pneumonia patients,which is beneficial for improving blood gas,reducing inflammatory reactions,promoting clinical symptom recovery,and improving disease prognosis.
Severe pneumoniaDopamineDobutamineBlood gas analysisInflammatory reactionsClinical symptom relief time
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