The Efficacy and Safety Analysis of Fiberoptic Bronchoscopy Combined with Bronchoalveolar Lavage and Cefoperazone Sulbactam in the Treatment of Elderly Patients with Bronchiectasis and Pulmonary Infection
Objective To analyze the effect of bronchoalveolar lavage(BAL)combined with cefoperazone sulbactam in elderly patients with bronchiectasis(BE)and pulmonary infection.Methods 60 elderly BE patients with pulmonary infection admitted to the hospital from January 2022 to August 2023 were selected as the research subjects.They were randomly divided into a control group and an observation group,with 30 cases in each group,using a random number table method.The control group received cefoperazone sulbactam,while the observation group received BAL and continued treatment for 2 weeks.Compare the clinical efficacy,symptom improvement,levels of inflammatory factors,lung function,and adverse reactions between two groups.Results The total effective rate of the observation group was 93.33%,which was higher than the control group's 73.33%,the fever relief time was(5.20±1.02)d,the cough disappearance time was(5.16±1.34)d,and the lung wet rale disappearance time was(7.35±1.63)d,which were shorter than the control group's(6.79±1.53)d,(6.83±1.69)d,and(9.76±2.05)d,and the differences between the groups were statistically significant(P<0.05).After treatment,the C-reactive protein was(11.39±1.05)mg/L,procalcitonin was(0.12±0.01)ng/mL,which was lower than the control group's(15.56±2.13)mg/L,(0.21±0.04)ng/mL,maximum ventilation volume was(69.96±7.48)L,maximum expiratory volume at 1 second was(2.26±0.84)L,lung capacity was(2.98±0.71)L,and which were greater than the control group's(61.47±6.20)L,(1.83±0.69)L,and(2.54±0.63)L,respectively,and the differences between the groups were statistically significant(P<0.05).No adverse reactions occurred during the treatment of 60 patients.Conclusion BAL combined with cefoperazone sulbactam can alleviate symptoms,alleviate inflammatory reactions,and improve lung function in elderly BE patients with pulmonary infection,and has certain application value.
BronchiectasiaPulmonary infectionAdverse reactionsPulmonary function
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