首页|神经内镜微创术对老年高血压性脑出血患者神经及炎性反应的影响

神经内镜微创术对老年高血压性脑出血患者神经及炎性反应的影响

扫码查看
原文链接
  • NETL
  • NSTL
  • 万方数据
目的 分析神经内镜微创术对老年高血压性脑出血(HICH)患者的影响.方法 选取 2022年 5 月—2023 年5月该院收治的 60 例老年HICH患者为研究对象,按随机数字表法将其分为对照组与观察组,各 30 例.对照组行小骨窗开颅术,观察组行神经内镜微创术,术后两组均随访 3 个月.对比两组患者的手术情况、神经因子、炎性反应及并发症发生情况.结果 观察组术中出血量为(68.96±5.31)mL,少于对照组的(131.43±7.46)mL,血肿清除率为 93.33%,高于对照组的 73.33%,手术时间为(65.34±5.29)min,住院时间为(12.46±2.57)d,均短于对照组的(106.82±8.31)min、(18.63±3.49)d,并发症发生率为 3.33%,低于对照组的 26.67%,组间差异有统计学意义(P＜0.05).术后 1 周,观察组神经元特异性烯醇化酶为(6.89±1.02)μg/L,S-100β蛋白为(0.13±0.01)ng/mL,P物质为(265.37±15.31)ng/L,C反应蛋白为(8.63±1.12)mg/L,白细胞介素-6 为(28.49±2.68)ng/L,肿瘤坏死因子-α 为(31.24±4.77)μg/L,均低于对照组的(10.53±1.56)μg/L、(0.36±0.05)ng/mL、(336.54±18.69)ng/L、(11.24±1.59)mg/L、(35.21±3.57)ng/L、(47.53±6.25)μg/L,组间差异有统计学意义(P＜0.05).结论 神经内镜微创术具有创伤小、血肿清除率高等优势,能够减轻神经功能损伤,控制炎性反应,且并发症少.
Effect of Minimally Invasive Neuroendoscopy Surgery on Nerve and Inflammatory Response in Elderly Patients with Hypertensive Intracerebral Hemorrhage
Objective To analyze the effect of minimally invasive neuroendoscopy surgery on elderly patients with hypertensive intracerebral hemorrhage(HICH).Methods 60 elderly patients with HICH treated in our hospital from May 2022 to May 2023 were selected as the study objects,and were divided a control group and an observation group according to random number table method,with 30 cases in each group.The control group underwent small bone window craniotomy,and the observation group underwent minimally invasive neuroendoscopy surgery.Both groups were followed up for 3 months.The operation status,neurofactors,inflammatory response and complications were compared between the two groups.Results The intraoperative blood loss in the observation group was(68.96±5.31)mL,less than(131.43±7.46)mL in the control group,the clearance rate of hematoma was 93.33%,higher than 73.33%in the control group,the operation time was(65.34±5.29)min,and the length of hospitalization was(12.46±2.57)d,were shorter than(106.82±8.31)min and(18.63±3.49)d in the control group,and the incidence of complications was 3.33%,lower than 26.67%in the control group,with statistical significance(P＜0.05).One week after operation,neuron-specific enolase,S-100β protein,substance P,C-reactive protein,Interleukin-6 and tumor necrosis factor-α in the observation group were(6.89±1.02)g/L,(0.13±0.01)ng/mL,(265.37±15.31)ng/L,(8.63±1.12)mg/L,(28.49±2.68)ng/L,(31.24±4.77)g/L,respectively,which were lower than(10.53±1.56)g/L,(0.36±0.05)ng/mL,(336.54±18.69)ng/L,(11.24±1.59)mg/L,(35.21±3.57)ng/L,(47.53±6.25)g/L of the control group,the differences between groups were statistically significant(P＜0.05).Conclusion Minimally invasive neuroendoscopy surgery has the advantages of small trauma and high hematoma clearance,which can reduce neurological damage,control inflammatory reaction,and has fewer complications.

Hypertensive intracerebral hemorrhage in the elderlyMinimally invasive neuroendoscopy surgeryInflamma-tory reactionComplications

张雷

展开 >

曹县人民医院神经外科,山东菏泽 274400

老年高血压性脑出血 神经内镜微创术 炎性反应 并发症

2024

反射疗法与康复医学

反射疗法与康复医学

ISSN：
年,卷(期)：2024.5(6)
  • 8