Application Effect of Dexmedetomidine Combined with Ropivacaine for Continuous Adductor Canal Block Analigesia in the Rehabilitation of Patients after Total Knee Arthroplasty
Objective To analyze the effect of dexmedetomidine combined with ropivacaine continuous adductor block analgesia on rehabilitation after total knee arthroplasty(TKA).Methods 90 patients receiving TKA surgery in the First People's Hospital of Changshu City from January 2021 to January 2023 were selected as the research objects and were divided into a control group and an observation group by random number table method,with 45 cases in each group.The control group was treated with 0.375%ropivacaine for ACB analgesia,while the observation group was treated with 1.0 μg/mL dexmedetomidine combined with 0.375%ropivacaine for ACB analgesia.The pain Aisual Analogue Scores(VAS)at 4,8,12,24 and 48 h after surgery,the time of first patient-controlled analgesia(PCA)pump,the number of PCA compressions,the dosage of flurbiprofen axidate,the time of first getting out of bed,the time of knee flexion to 90° and the occurrence of adverse reactions were compared between the two groups.Results At 4,8,12,24 and 48 h after surgery,the VAS scores of resting state and activity state in the observation group were lower than those in the control group,and the differences between the groups were statistically significant(P＜0.05).The first time of PCA compression in the observation group was longer than that in the control group,and the times of PCA compression and the dosage of flurbiprofen ester were less than those in the control group,and the differences between the groups were statistically significant(P＜0.05).The first time of getting out of bed and the time of knee flexage to 90°in the observation group were(40.39±4.26)h and(6.39±1.42)d,respectively,which were shorter than(59.54±7.79)h and(8.37±1.59)d in the control group,and the differences between the groups were statistically significant(P＜0.05).There were no significant differences in the incidences of adverse reactions between the two groups(P＞0.05).Conclusion Dexmedetomidine combined with ropivacaine ACB has a good analgesic effect,which can promote patients to get out of bed early after surgery and contribute to postoperative rehabilitation.
Total Knee ReplacementDexmedetomidineRopivacaineContinuous adductor Canal BlockRehabilitation
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