Effectiveness and Safety Analysis of Kangfuxin Liquid Combined with Rabeprazole Quadruple Therapy in the Treatment of Hp Positive Gastric Ulcers
Objective To explore the effectiveness and safety of Kangfuxin liquid combined with rabeprazole quadruple therapy in the treatment of Helicobacter pylori(Hp)positive gastric ulcers.Methods 78 Hp positive gastric ulcer patients admitted to Zoucheng People's Hospital from August 2021 to November 2023 were selected as the research objects and randomly divided into a control group and an observation group,with 39 cases in each group.The control group was treated with rabeprazole quadruple therapy,while the observation group was treated with Kangfu Xin liquid on the basis of the control group.Compare the clinical efficacy,Hp clearance rate,blood lipid levels,and adverse reactions between the two groups.Results The total effective rate and Hp clearance rate of the observation group were higher than those of the control group,and the differences were statistically significant(P＜0.05).After treatment,the levels of total cholesterol,triglycerides,and low-density lipoprotein cholesterol in the observation group were lower than those in the control group,while the levels of high-density lipoprotein cholesterol were higher than those in the control group.The differences between the groups were statistically significant(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The use of Kangfuxin liquid combined with rabeprazole quadruple therapy in Hp positive gastric ulcer patients can significantly enhance the therapeutic effect,effectively eradicate Hp,improve blood lipid levels,and have high medication safety.
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