首页|输尿管软镜钬激光碎石与体外冲击波治疗输尿管上段结石的对比分析

输尿管软镜钬激光碎石与体外冲击波治疗输尿管上段结石的对比分析

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目的 比较输尿管软镜钬激光碎石(FURL)、体外冲击波(ESWL)对输尿管上段结石患者的影响.方法 选取2021 年 7 月—2023 年 7 月青县人民医院收治的 84 例输尿管上段结石患者为研究对象,按随机数字表法将其分为对照组和观察组,每组 42 例.对照组行ESWL,观察组行FURL.对比两组患者的结石清除率、应激反应、炎症反应、肾功能及并发症发生情况.结果 观察组的结石清除率为 95.24%,高于对照组的 80.95%,差异有统计学意义(P<0.05).术后,观察组的降钙素原、C反应蛋白水平分别为(0.56±0.16)ng/mL、(7.61±1.01)mg/L,均低于对照组的(0.79±0.24)ng/mL、(10.53±1.46)mg/L,组间差异有统计学意义(P<0.05).术后,观察组的尿素氮、血肌酐水平分别为(7.15±1.03)mmol/L、(71.21±5.15)μmol/L,均低于对照组的(8.96±1.56)mmol/L、(85.76±5.92)μmol/L,组间差异有统计学意义(P<0.05).术前、术后,两组的各项应激反应指标水平比较,组间差异无统计学意义(P>0.05).观察组的并发症发生率为 4.76%,低于对照组的21.43%,差异有统计学意义(P<0.05).结论 与ESWL相比,FURL可提高结石清除率,其引起的炎症反应更轻,对输尿管上段结石患者的肾功能损伤较小,且并发症更少,具有一定的应用价值,可在临床推广使用.
Comparative Analysis of Flexible Ureteroscopic Lithotripsy and Extracorporeal Shock Wave Lithotripsy for Upper Ureteral Calculi
Objective To compare the effects of flexible ureteroscopic lithotripsy(FURL)and extracorporeal shock wave lithotripsy(ESWL)on patients with upper ureteral calculi.Methods 84 patients with upper ureteral calculi treated in Qing County People's Hospital from July 2021 to July 2023 were selected as the research objects and were divided into a control group and an observation group according to random number table method,with 42 cases in each group.The control group received ESWL and the observation group received FURL.The calculus clearance rate,stress response,inflammation response,renal function and complications were compared between the two groups.Results The calculus clearance rate of observation group was 95.24%,higher than 80.95%of control group,the difference was statistically significant(P<0.05).After operation,the levels of procalcitonin and C-reactive protein in the observation group were(0.56±0.16)ng/mL and(7.61±1.01)mg/L,respectively,which were lower than(0.79±0.24)ng/mL and(10.53±1.46)mg/L in the control group,the differences between the groups were statistically significant(P<0.05).After operation,the levels of blood urea nitrogen and serum creatinine in the observation group were(7.15±1.03)mmol/L and(71.21±5.15)μmol/L,respectively,which were lower than(8.96±1.56)mmol/L and(85.76±5.92)μmol/L in the control group,the differences between the groups were statistically significant(P<0.05).Before and after surgery,there were no significant differences in the levels of stress response indexes between the two groups(P>0.05).The incidence of complications in the observation group was 4.76%,lower than 21.43%in the control group,and the difference was statistically significant(P<0.05).Conclusion Compared with ESWL,FURL can improve the calculus clearance rate,cause less inflammatory reaction,and cause less renal damage and complications in patients with upper ureteral calculi.FURL has certain application value and can be widely used in clinic.

Upper ureteral calculiStress responseInflammatory responseRenal functionComplications

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青县人民医院泌尿外科,河北沧州 062650

输尿管上段结石 应激反应 炎症反应 肾功能 并发症

2024

反射疗法与康复医学

反射疗法与康复医学

ISSN:
年,卷(期):2024.5(7)