Effects of Anatomic Laparoscopic Hepatectomy on Stress Indexes and Liver Function in Patients with Primary Hepatic Carcinoma
Objective To evaluate the clinical value of anatomic laparoscopic hepatectomy(ALH)in patients with primary hepatic carcinoma(PHC).Methods A total of 62 patients with PHC admitted to our hospital from January 2022 to November 2023 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 31 cases in each group.The control group was treated with nonanatomic laparoscopic hepatectomy,and the observation group was treated with ALH.The operation status,stress indexes,liver function and complications were compared between the two groups.Results The blood transfusion volume and intraoperative blood loss in the observation group were(175.63±13.51)mL and(263.52±24.14)mL,respectively,which were less than(191.58±14.83)mL and(281.69±25.43)mL in the control group,and the postoperative hospitalization time was(8.23±1.15)d,which was shorter than(9.31±1.19)d in the control group,and the differences between groups were statistically significant(P＜0.05).The levels of norepinephrine,cortisol and adrenocorticotropin in the observation group were(189.14±15.59)ng/L,(169.62±15.74)μg/L and(10.09±1.23)ng/L,respectively,which were lower than(211.53±20.83)ng/L,(188.36±16.75)μg/L and(12.92±1.35)ng/L of the control group,and the differences between groups were statistically significant(P＜0.05).The postoperative levels of total bilirubin,aspartate aminotransferase and alanine aminotransferase in the observation group were(19.55±1.51)μmol/L,(46.58±4.17)U/L and(65.96±6.17)U/L,respectively,which were lower than(22.07±2.04)μmol/L,(52.41±5.38)U/L,(71.25±6.26)U/L of the control group,and the differences between groups were statistically significant(P＜0.05).There was no significant difference in the incidence of complications between the two groups(P＞0.05).Conclusion ALH is more effective in the treatment of PHC,can reduce surgical trauma,reduce stress response,reduce liver function damage,and is safe and reliable.
Primary hepatic carcinomaAnatomic laparoscopic hepatectomyStress indexexLiver function
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