首页|维生素AD滴剂联合普米克令舒对毛细支气管炎患儿症状改善及血清学指标的影响

维生素AD滴剂联合普米克令舒对毛细支气管炎患儿症状改善及血清学指标的影响

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目的 探究维生素AD滴剂联合普米克令舒对毛细支气管炎患儿症状改善及血清学指标的影响.方法 选择2021 年 6 月—2023 年 6 月济宁市第三人民医院收治的 118 例毛细支气管炎患儿为研究对象,按随机数字表法将其分为对照组和观察组,各 59 例.对照组给予普米克令舒治疗,观察组给予维生素AD滴剂联合普米克令舒治疗.对比两组患儿的血清学指标、症状改善时间、肺功能和不良反应情况.结果 观察组肺部哮鸣音、喘息、气促、咳嗽症状消失时间均短于对照组,组间差异有统计学意义(P<0.05);治疗后,观察组半胱氨酸白三烯、单核细胞趋化蛋白-1 水平均低于对照组,γ-干扰素水平高于对照组,组间差异有统计学意义(P<0.05);治疗后,观察组用力肺活量、第一秒用力呼气容积、呼气峰值流速水平均大于对照组,组间差异有统计学意义(P<0.05);两组不良反应发生率对比,差异无统计学意义(P>0.05).结论 维生素AD滴剂联合普米克令舒治疗毛细支气管炎患儿,有助于加快其临床症状消退,改善患儿血清学指标,提高肺功能,且安全性良好,值得推广.
Effect of Vitamin AD Drops Combined with Pulmicort on Symptom Improvement and Serological Indicators in Children with Bronchiolitis
Objective To investigate the effect of vitamin AD drops combined with pulmicort on symptom improvement and serological indicators in children with bronchiolitis.Methods A total of 118 children with bronchiolitis admitted to the Third People's Hospital of Jining City from June 2021 to June 2023 were selected as the research subjects,divided into a control group and an observation group using a random number table method,with 59 cases in each group.The control group received treatment with pulmicort,while the observation group received treatment with Vitamin AD drops combined with pulmicort.Compare the serological indicators,symptom improvement time,lung function,and adverse reactions between two groups of pediatric patients.Results The disappearance time of lung wheezing,wheezing,shortness of breath,and cough symptoms in the observation group was shorter than that in the control group,the differences between groups were statistically significant(P<0.05);after treatment,the levels of cysteinyl leukotrienes and monocyte chemotactic protein-1 in the observation group were lower than those in the control group,while the levels of γ-interferon were higher than those in the control group,the differences between groups were statistically significant(P<0.05);after treatment,the observation group had greater levels of forced vital capacity,first second forced expiratory volume,and peak expiratory flow rate compared to the control group,the differences between groups were statistically significant(P<0.05);comparison of adverse reactions between two groups,the differences was not statistically significant(P>0.05).Conclusion The combination of vitamin AD drops and pulmicort in the treatment of children with bronchiolitis is helpful in accelerating the resolution of clinical symptoms,improving serological indicators,enhancing lung function,and has good safety.It is worth promoting.

BronchiolitisChildrenVitamin AD dropsPulmicortSymptom improvementSerological indicators

艾凤庭、刘艳春

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济宁市第三人民医院(兖州区人民医院)儿科,山东济宁 272100

毛细支气管炎 患儿 维生素AD滴剂 普米克令舒 症状改善 血清学指标

2024

反射疗法与康复医学

反射疗法与康复医学

ISSN:
年,卷(期):2024.5(9)