首页|宁泌泰胶囊联合左氧氟沙星治疗对慢性前列腺炎患者前列腺液中炎性因子及免疫功能的影响

宁泌泰胶囊联合左氧氟沙星治疗对慢性前列腺炎患者前列腺液中炎性因子及免疫功能的影响

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目的 探讨宁泌泰胶囊联合左氧氟沙星治疗慢性前列腺炎(CP)患者的效果.方法 选择 2020 年 5 月—2023 年 5月该院收治的 80 例CP患者为研究对象,按随机数字表法将其分为对照组和治疗组,各40 例.对照组实施左氧氟沙星治疗,治疗组在对照组基础上联合宁泌泰胶囊治疗,两组均持续治疗 1 个月.对比两组的临床疗效、炎性因子、免疫功能及症状缓解时间.结果 治疗后,治疗组临床总有效率为 92.50%,高于对照组的 75.00%,差异有统计学意义(P<0.05);治疗组白细胞介素-1、肿瘤坏死因子-α、TNF-血管细胞黏附因子水平均低于对照组,组间差异有统计学意义(P<0.05);治疗组白细胞分化抗原(CD)4+、CD4+/CD8+水平均高于对照组,组间差异有统计学意义(P<0.05);治疗组症状缓解时间短于对照组,差异有统计学意义(P<0.05).结论 对CP患者实施左氧氟沙星、宁泌泰胶囊联合治疗的疗效显著,能改善患者的免疫功能,降低前列腺液中的炎性因子水平,缩短症状缓解时间.
Effect of Ningmitai Capsules Combined with Levofloxacin Treatment on Inflammatory Factors and Immune Function in Prostate Fluid of Patients with Chronic Prostatitis
Objective Exploring the efficacy of Ningmitai capsules combined with levofloxacin in the treatment of patients with chronic prostatitis(CP).Methods Selecting 80 CP patients admitted to the hospital from May 2020 to May 2023 as the research subjects,and they were divided into a control group and a treatment group using a random number table method,with 40 cases in each group.The control group received treatment with levofloxacin,while the treatment group received treatment in combination with Ningmitai capsules on the basis of the control group.Both groups received continuous treatment for one month.Compare the clinical efficacy,inflammatory factors,immune function,and symptom relief time between two groups.Results After treatment,the total clinical effective rate of the treatment group was 92.50%,which was higher than 75.00%of the control group,the differences was statistically significant(P<0.05);the levels of Interleukin-1,tumor necrosis factor-α,and TNF-vascular cell adhesion factor in the treatment group were lower than those in the control group,the differences between groups were statistically significant(P<0.05);the levels of Cluster of Differentiation(CD)4+and CD4+/CD8+in the treatment group were higher than those in the control group,the differences between groups were statistically significant(P<0.05);the symptom relief time in the treatment group was shorter than that in the control group,the differences was statistically significant(P<0.05).Conclusion The combined treatment of levofloxacin and Ningmitai capsules for CP patients has a significant therapeutic effect,which can improve the patient's immune function,reduce the level of inflammatory factors in prostate fluid,and shorten the time for symptom relief.

Chronic prostatitisNingmitai capsulesLevofloxacinInflammatory factorsImmunologic function

孙士虎

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滕州市妇幼保健院男性生殖科,山东滕州 277500

慢性前列腺炎 宁泌泰胶囊 左氧氟沙星 炎性因子 免疫功能

2024

反射疗法与康复医学

反射疗法与康复医学

ISSN:
年,卷(期):2024.5(9)