Effect of Clopidogrel Combined with Rosuvastatin on Cardiac Function and Blood Lipid Levels in Patients with Coronary Heart Disease and Angina Pectoris
Objective Exploring the impact of clopidogrel combined with rosuvastatin treatment on patients with coronary heart disease and angina pectoris.Methods Eighty-four patients with coronary heart disease and angina pectoris admitted to our hospital from July 2020 to July 2023 were selected as the research subjects,they were divided into a control group and an observation group using a random number table method,with 42 cases in each group.The control group was treated with clopidogrel,while the observation group was treated with clopidogrel combined with rosuvastatin.Both groups were treated for 8 weeks.Compare the clinical efficacy,cardiac function indicators,blood lipid levels,and incidence of adverse reactions between two groups.Results After treatment,the total effective rate of the observation group was higher than that of the control group,and the levels of cardiac index and ejection fraction were higher than those of the control group,the differences between groups were statistically significant(P＜0.05).The serum total cholesterol,triglycerides,and low-density lipoprotein cholesterol levels in the observation group were all lower than those in the control group,while high-density lipoprotein cholesterol levels were higher than those in the control group,the differences between groups were statistically significant(P＜0.05).Comparison of incidence rates of adverse reactions between two groups,the differences was not statistically significant(P＞0.05).Conclusion The efficacy of clopidogrel combined with rosuvastatin in treating patients with coronary heart disease and angina pectoris is definite.It can regulate blood lipid levels,improve heart function in patients,and has high safety.
Coronary heart disease and angina pectorisClopidogrelRosuvastatinHeart functionBlood lipid levels
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