Effects of Aspirin and Clopidogrel Combined with Shuxuetong Treatment on Hemorheological Indicators,Neurological Function and Safety In Patients with Acute Cerebral Infarction
Objective Exploring the effects of aspirin and clopidogrel combined with Shuxuetong treatment on patients with acute cerebral infarction(ACI).Methods Eighty-two ACI patients admitted to Lanling County People's Hospital February 2021 to October 2023 were selected as the research subjects,according to the random number table method,they were divided into a control group and an observation group,with 41 cases in each group.The control group was treated with aspirin and clopidogrel,while the observation group was treated with Shuxuetong in addition to the control group.Compare two groups of hemorheological indicators,neurological function,quality of life,and adverse reactions.Results After 14 days of treatment,the observation group had a whole blood low shear viscosity of(9.57±0.74)mPa·s,plasma viscosity of(1.58±0.11)mPa·s,fibrinogen of(3.01±0.03)g/L,whole blood high shear viscosity of(4.93±0.77)mPa·s,and National Institutes of Health Stroke Scale of(7.22±1.08)points,all of which were lower than the control group's(10.87±0.82)mPa·s,(1.71±0.14)mPa·s,and(4.52±0.07)g/L.(6.15±0.81)mPa·s,(9.84±2.76)points,the differences between groups were statistically significant(P＜0.05);the overall health score in the 36-item Short Form Health Surve was(70.28±5.31)points,physiological function score was(71.58±5.88)points,physical pain score was(70.25±5.94)points,and vitality score was(73.68±5.19)points,all higher than the control group's(59.78±4.51)points,(58.44±4.69)points,(60.87±4.47)points,and(52.87±4.49)points,the differences between groups were statistically significant(P＜0.05);comparison of incidence of adverse reactions between two groups,the difference was not statistically significant(P＞0.05).Conclusion The combination of aspirin and clopidogrel combined with Shuxuetong in the treatment of ACI patients has a significant effect,which can reduce the degree of nerve damage,improve the hemorheological indicators in the body,improve the quality of life of patients,and will not increase adverse reactions,with high safety.
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