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小儿热速清颗粒联合布地奈德治疗急性上呼吸道感染患儿的临床效果观察

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目的 探讨小儿热速清颗粒联合布地奈德治疗急性上呼吸道感染患儿的临床效果观察.方法 选取2021年4月—2022年 12 月济宁市兖州区中医医院收治的 104 例急性上呼吸道感染患儿为研究对象,按随机数字表法将其分为对照组和观察组,每组 52 例.对照组采用布地奈德治疗,观察组在对照组基础上联合小儿热速清颗粒治疗.对比两组临床疗效、症状缓解时间、炎性因子指标、不良反应发生情况.结果 观察组的治疗总有效率为 96.15%,高于对照组的84.62%,差异有统计学意义(P<0.05).治疗后,观察组发热、肺啰音、咳嗽、喉咙肿痛消失时间均短于对照组,血清白细胞介素-8、血清白细胞介素-6、C-反应蛋白、肿瘤坏死因子水平均低于对照组,组间差异有统计学意义(P<0.05).两组不良反应发生率对比,差异无统计学意义(P>0.05).结论 小儿热速清颗粒联合布地奈德在急性上呼吸道感染患儿的治疗中疗效显著,能够有效促进其临床症状缓解,降低患儿血清炎性因子水平,且具有较好的安全性.
Clinical Observation of Xiaoer Resuqing Granule Combined with Budesonide in the Treatment of Children with Acute Upper Respiratory Tract Infection
Objective To investigate the clinical effect of Xiaoer Resuqing Granule combined with budesonide in the treatment of children with acute upper respiratory tract infection.Methods A total of 104 children with acute upper respiratory tract infection admitted to Jining City Yanzhou District Hospital of Traditional Chinese Medicine from April 2021 to December 2022 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 52 cases in each group.The control group was treated with budesonide,and the observation group was treated with Xiaoer Resuqing granule on the basis of the control group.Clinical effect,symptom remission time,inflammatory factor index and occurrence of adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 96.15%,which was higher than 84.62%in the control group,and the difference was statistically significant(P<0.05).After treatment,fever,pulmonary rale,cough and sore throat disappeared in observation group less than control group,serum interleukin-8,serum interleukin-6,C-reactive protein and tumor necrosis factor levels were lower than those in the control group,and the differences between the groups were statistically significant(P<0.05).The incidence of adverse reactions between the two groups was compared,and the difference was no statistically significant(P>0.05).Conclusion Xiaoer Resuqing Granule combined with budesonide is effective in the treatment of children with acute upper respiratory tract infection,can effectively promote the alleviation of clinical symptoms,reduce the level of serum inflammatory factors in children,and has a good safety.

Acute upper respiratory tract infectionResuqing granuleBudesonideClinical effectAdverse reaction

王强

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济宁市兖州区中医医院儿内科,山东济宁 272100

急性上呼吸道感染 热速清颗粒 布地奈德 临床疗效 不良反应

2024

反射疗法与康复医学

反射疗法与康复医学

ISSN:
年,卷(期):2024.5(11)