反射疗法与康复医学2024，Vol.5Issue(11) ：80-82,94.

生酮饮食结合运动康复训练对非酒精性脂肪性肝病患者脂代谢及肝功能的影响

Effects of Ketogenic Diet Combined with Exercise Rehabilitation Training on Lipid Metabolism and Liver Function in Patients with Non-Alcoholic Fatty Liver Disease

张昌义 曲效磊
反射疗法与康复医学2024，Vol.5Issue(11) ：80-82,94.
✕
  • 万方数据

生酮饮食结合运动康复训练对非酒精性脂肪性肝病患者脂代谢及肝功能的影响

Effects of Ketogenic Diet Combined with Exercise Rehabilitation Training on Lipid Metabolism and Liver Function in Patients with Non-Alcoholic Fatty Liver Disease

张昌义 1曲效磊2
扫码查看

作者信息

  • 1. 山东中医药大学附属青岛市即墨区中医医院消化内科,山东青岛 266200
  • 2. 山东中医药大学附属青岛市即墨区中医医院肛肠科,山东青岛 266200
  • 折叠

摘要

目的 探讨生酮饮食结合运动康复训练对非酒精性脂肪性肝病(NAFLD)患者脂代谢及肝功能的影响.方法 选取山东中医药大学附属青岛市即墨区中医医院 2022 年 2 月—2023 年 2 月收治的 72 例NAFLD患者为研究对象,按照随机数字表法将其分为对照组和观察组,每组 36 例.对照组采用运动康复训练干预,观察组在对照组基础上采用生酮饮食管理干预,两组均持续干预 3 个月.比较两组患者的临床疗效、脂代谢与肝功能.结果 观察组治疗总有效率为94.44%,高于对照组的75.00%,差异有统计学意义(P<0.05).治疗前,两组总胆固醇、低密度脂蛋白胆固醇比较,组间差异无统计学意义(P＞0.05);治疗后,观察组总胆固醇为(1.68±0.30)mmol/L,低密度脂蛋白胆固醇为(1.50±0.34)mmol/L,均低于对照组的(2.19±0.21)mmol/L,(2.50±0.14)mmol/L,组间差异有统计学意义(P<0.05).治疗前,两组丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)比较,组间差异无统计学意义(P＞0.05);治疗后,观察组ALT为(93.48±6.94)U/L,AST为(54.36±10.06)U/L,均低于对照组的(101.24±18.28)U/L,(86.41±6.89)U/L,组间差异有统计学意义(P<0.05).结论 生酮饮食结合运动康复训练可以提高NAFLD患者的临床疗效,改善脂代谢和肝功能.

Abstract

Objective To investigate the effects of ketogenic diet combined with exercise rehabilitation training on lipid metabolism and liver function in patients with non-alcoholic fatty liver disease(NAFLD).Methods A total of 72 patients with NAFLD admitted to the Qingdao Jimo District Hopsital of Traditional Chinese Medicine Affiliated to Shandong University of Traditional Chinese Medicine from February 2022 to February 2023 were selected as the research objects.They were divided into a control group and an observation group according to random number table method,36 cases in each group.The control group was treated with exercise rehabilitation training intervention,and the observation group was treated with ketogenic diet management intervention on the basis of the control group,the intervention lasted for 3 months in both groups.The clinical efficacy,lipid metabolism and liver function of the two groups were compared.Results The total effective rate of the observation group was 94.44%,higher than 75.00%of the control group,and the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in total cholesterol and low density lipoprotein cholesterol between the two groups(P＞0.05);after treatment,the total cholesterol and low density lipoprotein cholesterol in the observation group were(1.68±0.30)mmol/L and(1.50±0.34)mmol/L respectively,which were lower than(2.19±0.21)mmol/L and(2.50±0.14)mmol/L in the control group,and the differences between groups were statistically significant(P<0.05).Before treatment,there were no significant differences in alanine aminotransferase(ALT)and aspartate aminotransferase(AST)between the two groups(P＞0.05);after treatment,the ALT and AST in the observation group were(93.48±6.94)U/L and(54.36±10.06)U/L,which were lower than(101.24±18.28)U/L and(86.41±6.89)U/L in the control group,and the differences between groups were statistically significant(P<0.05).Conclusion Ketogenic diet combined with exercise rehabilitation training can improve the clinical efficacy,lipid metabolism and liver function of NAFLD patients.

关键词

非酒精性脂肪性肝病/生酮饮食/运动康复训练/脂代谢/肝功能

Key words

Non-alcoholic fatty liver disease/Ketogenic diet/Exercise rehabilitation training/Lipid metabolism/Liver function

引用本文复制引用

基金项目

山东省中医药科技项目(2021M117)

出版年

2024
反射疗法与康复医学

反射疗法与康复医学

ISSN：
段落导航相关论文