Effects of Yanhuning Combined with Montelukast Sodium on Clinical Symptoms,Inflammatory Indicators and Immune Function of Children with Acute Bronchitis
Objective To investigate the effects of Yanhuning combined with montelukast sodium on clinical symptoms,inflammatory indicators and immune function of children with acute bronchitis.Methods A total of 84 children with acute bronchitis admitted to Changqing District People's Hospital of Jinan City from January 2019 to December 2023 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 42 cases in each group.The control group received treatment with montelukast sodium,and the observation group received combined treatment with Yanhuning on the basis of the control group,both groups were treated for 1 week.The time of clinical symptom disappearance,inflammatory indicators,immune function and occurrence of adverse reactions were compared between the two groups.Results The disappearance time of lung moist rales,cough and expectoration in the observation group were shorter than those in the control group,and the difference was statistically significant(P<0.05).After treatment,interleukin-6,interleukin-8,interleukin-1β,tumor necrosis factor-α and CD8+in two groups were lower than before treatment,and the observation group were lower than control group,the difference was statistically significant(P<0.05);CD4+,CD3+and CD4+/CD8+in both groups were higher than before treatment,and the observation group were higher than control group,the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion Yanhuning combined with Montelukast sodium in the treatment of acute bronchitis children,can effectively improve the clinical symptoms and inflammatory indicators,enhance the immune function of children,and the adverse reaction rate is low,good safety.
Acute bronchitisYanhuningMontelukast sodiumClinical symptomsInflammatory indicatorsImmune function
万方数据
