Clinical Effect of Hip Joint Surgical Dislocation and Bone Grafting Combined with Compound Danshen Chuanxiong Formula in the Treatment of Early and Mid Stage Osteonecrosis of Femeral Head
Objective Analyze the effect of hip joint surgical dislocation and bone grafting combined with compound Danshen Chuanxiong formula treatment on patients with early and mid stage osteonecrosis of femeral head.Methods Prospective collection of 60 hospitalized patients with early to mid stage osteonecrosis of femeral head in the Guangxi Guigang Integrated Traditional Chinese and Western Medicine Orthopedic Hospital from July 2022 to July 2025 were selected as the research objects,divided into a control group and an observation group using simple sampling method,with 30 cases in each group.The control group was treated with hip joint surgical dislocation and bone grafting,while the observation group was treated with hip joint surgical dislocation and bone grafting combined with compound Danshen Chuanxiong formula.The clinical treatment effects of the two groups were compared.Results The total effective rate of the observation group was 90.00％,which was higher than 70.00％of the control group,and the difference was statistically significant(P<0.05).After 6 months of treatment,the blood osteopontin level(49.35±10.16)ng/mL in the observation group was higher than(43.29±10.21)ng/mL in the control group,while the osteoprotegerin level(322.04±88.14)pg/mL,osteocalcin level(28.11±2.34)ng/mL,and type Ⅰ collagen C-terminal peptide level(0.51±0.11)μg/L were all lower than(389.76±89.66)pg/mL,(33.44±2.21)ng/mL,and(0.86±0.15)μg/L in the control group,with statistically significant differences between the groups(P<0.05);the plasma viscosity(1.63±0.26)mPa·s,whole blood high shear viscosity(5.64±1.04)mPa·s,whole blood low shear viscosity(12.11±2.35)mPa·s,and red blood cell aggregation index(2.43±0.32)in the observation group were significantly lower than(1.88±0.31)mPa·s,(8.63±1.66)mPa·s,(18.49±3.36)mPa·s,and(2.88±0.45)in the control group,with statistically significant differences between the groups(P<0.05).After 6 and 8 months of treatment,the scores of Harris Hip Function scale and Japanese Orthopedic Association in the observation group were higher than those in the control group,and the differences between the groups were statistically significant(P<0.05).Conclusion Hip joint surgical dislocation and bone grafting combined with compound Danshen Chuanxiong formula can significantly improve the therapeutic effect,bone metabolism indicators,hemorheology indicators,and hip joint function in patients with early and mid stage osteonecrosis of femeral head.It is recommended.
Osteonecrosis of femeral headHip joint surgical dislocation and bone graftingCompound Danshen Chuanxiong formulaBone metabolism indicatorsHip joint function
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