Effect Analysis of Budesonide Formoterol Inhalation Powder Aerosol and Tiotropium Bromide Powder Aerosol in the Treatment of Patients with Chronic Obstructive Pulmonary Disease
Objective To investigate the therapeutic effect of budesonide formoterol inhalation powder aerosol and tiotropium bromide powder aerosol in patients with chronic obstructive pulmonary disease(COPD).Methods A total of 86 COPD patients admitted to Renhuai People's Hospital from January 2022 to February 2024 were selected as the research objects,and they were divided into control group and observation group according to random number table method,with 43 cases in each group.The control group was treated with tiotropium bromide powder aerosol,and the observation group was treated with budesonide formoterol inhalation powder aerosol combined with tiotropium bromide powder aerosol,both groups received continuous treatment for 4 weeks.The clinical efficacy,lung function,quality of life and occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 95.35%,which was higher than 81.40%of the control group,and the difference was statistically significant(P<0.05).After treatment,forced expiratory volume(FEV1)and forced vital capacity(FVC)at the first second in both groups were higher than those before treatment,and FEV1/FVC were higher than those before treatment,and FEV1 and FVC in the observation group were higher than those in the control group,and FEV1/FVC was higher than that in the control group,the difference were statistical significance(P<0.05);both groups of St.George's Respiratory Questionnaire scores were lower than those before treatment,and the observation group was lower scores than that in the control group,the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The treatment of budesonide formoterol inhalation powder aerosol and tiotropium bromide powder aerosol can improve the pulmonary function,stabilize the condition and improve the quality of life of patients with COPD,without significantly increasing adverse reactions,and is safe and reliable.
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