Effects of Combination Therapy of Aspirin and Butadiphthalein Softgel on Hemodynamic Indexes and Neurological Function in Patients with Ischemic Stroke
Objective To investigate the effect of aspirin combined with butadiphthalein capsule on patients with ischemic stroke(CIS).Methods Ninety-two CIS patients admitted to the Second People's Hospital of Binzhou City from August 2021 to October 2023 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 46 cases in each group.The control group was treated with aspirin enteric-coated tablets,and the observation group was treated with butylphthalein capsule on the basis of the control group.The clinical efficacy,neurological function,hemodynamic indexes and the occurrence of adverse reactions were compared between the two groups.Results The total effective rate of observation group was 93.48%,which was higher than 78.26%of the control group,the difference was statistically significant(P<0.05).After treatment,the score of the National Institutes of Health Stroke Scale in both groups were lower than those before treatment,and the observation group was lower than that in the control group,the difference was statistically significant(P<0.05);the average cerebral artery flow velocity and maximum peak flow velocity in both groups were faster than those before treatment,and the observation group were faster than those of the control group,and the vascular resistance index in both groups were lower than those before treatment,and the observation group was lower than that in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The use of aspirin combined with butylphthalein capsule in CIS patients can enhance the therapeutic effect,improve nerve function,effectively regulate hemodynamics,and have high drug safety.
Ischemic strokeAspirinButylphthaleinHemodynamic indexesNeurological function
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