Effect of Laparoscopic Cholecystectomy on Stress Response Indicators and Gastrointestinal Hormone Levels in Patients with Gallstones
Objective To explore the effects of laparoscopic cholecystectomy on stress response indicators and gastrointestinal hormone levels in patients with gallstones.Methods A total of 120 patients with gallstones from Jinxiang County People's Hospital from October 2022 to October 2023 were selected as the research objects and randomly divided into a control group and an observation group using a random number table method,with 60 patients in each group.The control group underwent open cholecystectomy,while the observation group underwent laparoscopic cholecystectomy.Compare perioperative indicators,stress response indicators,gastrointestinal hormone levels,and postoperative complications between two groups.Results The observation group had shorter surgical time,first postoperative exhaust time,first postoperative time getting out of bed,and hospitalization time compared to the control group,and the differences between the groups were statistically significant(P<0.05).Three days after surgery,the white blood cell count(WBC),fasting blood glucose(FBG),and cortisol(Cor)levels in both groups increased compared to preoperative levels,but the WBC,FBG,and Cor levels in the observation group were lower than those in the control group,with statistical significance(P<0.05);the levels of gastrin and motilin in both groups improved on average compared to preoperative levels,and the observation group had lower levels of gastrin and higher levels of motilin than the control group,with statistical significance(P<0.05).The incidence of postoperative complications in the observation group was 5.00%,which was lower than 16.67%in the control group,and the difference was statistically significant(P<0.05).Conclusion Laparoscopic cholecystectomy for patients with gallstones can reduce perioperative indicators and stress response indicators levels,improve gastrointestinal hormone levels,and reduce the incidence of complications.
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